Protein Alignment CG4653 and KLK12

DIOPT Version :9

• Sequence 1: NP_573150.2
• Gene: CG4653 / 32650
• FlyBaseID: FBgn0030776
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 64/237 - (27%)
• Similarity: 104/237 - (43%)
• Gaps: 28/237 - (11%)

  Fly    12 LLLLVVIVTLGVVQSSRLP-----AEVG--SQPHSISLRRNGVHVCGGALIREKWILTAAHCVSL 69
            |.:.:::..||:.|:: .|     .|.|  |||..:.|.......|||.||..:|:||||||
Human     3 LSIFLLLCVLGLSQAA-TPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHC--- 63

  Fly    70 GGGQQSYPAKSYNVRVG--SIQRLTGGQLVPLSKI-IIHTNYSSSDAVGSNDLALLELETSVVLN 131
                   ....|.||:|  |:.:|...:.:..|.. :.|..|..:.....:||.||.|...|.:.
Human    64 -------SGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVT 121

  Fly   132 ANTNPIDLATERPAAGSQIIFSGWG-SSQVDGSLSHVLQVATRQSLSASDCQTELYLQQ--EDLL 193
            ::..|:.|..:...||::...|||| ::........:||......:|.:.|. .:|..:  .:::
Human   122 SSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCH-GVYPGRITSNMV 185

  Fly   194 CLSPVDEDFAGLCSGDAGAPASYNNQLVGIAAF-FVSGCGSE 234
            |...|....|  |.||:|.|......|.|:.:: .|..||.:
Human   186 CAGGVPGQDA--CQGDSGGPLVCGGVLQGLVSWGSVGPCGQD 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	60/219 (27%)
		Tryp_SPc	30..249	CDD:214473	60/219 (27%)
KLK12	NP_062544.1	Tryp_SPc	21..236	CDD:214473	59/218 (27%)
		Tryp_SPc	22..236	CDD:238113	59/217 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010