Protein Alignment CG4653 and KLK14

DIOPT Version :10

• Sequence 1: NP_573150.2
• Gene: CG4653 / 32650
• FlyBaseID: FBgn0030776
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_071329.3
• Gene: KLK14 / 43847
• HGNCID: 6362
• Length: 251
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 64/273 - (23%)
• Similarity: 114/273 - (41%)
• Gaps: 63/273 - (23%)

  Fly    12 LLLLVVIVTLGVVQSSRLPAEV--------GSQPHSISL----RRNGVHVCGGALIREKWILTAA 64
            ||..:.::.:.:.||.....::        .|||...:|    ||.  .:|||||:..:|::|||
Human     4 LLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRR--FLCGGALLSGQWVITAA 66

  Fly    65 HC------VSLGGGQQSYPAKSYNVRVGSIQRLTGGQLVPLSKIIIHTNYSSSDAVGSNDLALLE 123
            ||      |:||         .:|:|.....:    |::.:.:.:.|.||:|  ....|||.||:
Human    67 HCGRPILQVALG---------KHNLRRWEATQ----QVLRVVRQVTHPNYNS--RTHDNDLMLLQ 116

  Fly   124 LETSVVLNANTNPIDLATERPAAGSQIIFSGWGS--------------SQVDGSLSHVLQVATRQ 174
            |:....:.....||::.....:.|:....||||:              ..::.|...|.|.|..:
Human   117 LQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPR 181

  Fly   175 SLSASDCQTELYLQQEDLLCLSPVDEDFAGLCSGDAGAPASYNNQLVGIAAFFVSGCG-SEQPDG 238
            :::..            ::| :.|.:.....|.||:|.|.....||.|:.::.:..|. ...|..
Human   182 TITPG------------MVC-AGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGV 233

  Fly   239 YVDVTQHLEWINE 251
            |.::.::..||.|
Human   234 YTNLCKYRSWIEE 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	60/255 (24%)
KLK14	NP_071329.3	Tryp_SPc	25..247	CDD:238113	60/252 (24%)