DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4653 and CG9733

DIOPT Version :9

Sequence 1:	NP_573150.2	Gene:	CG4653 / 32650	FlyBaseID:	FBgn0030776	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_651784.2	Gene:	CG9733 / 43601	FlyBaseID:	FBgn0039759	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	254	Identity:	69/254 - (27%)
Similarity:	109/254 - (42%)	Gaps:	40/254 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 EVGSQPHSISL---RRNG---VHVCGGALIREKWILTAAHCVSLGGGQQSYPAKSYNVRVGSIQR 90
            :|...|..:.|   ||:|   ...|.|:||..:::||||||  |.|..:.......:||:|....
  Fly   169 DVNEFPWMVLLEYRRRSGNGLSTACAGSLINRRYVLTAAHC--LTGRIEREVGTLVSVRLGEHDT 231

  Fly    91 LT-------GGQLVP------LSKIIIHTNYSSSDAVGSNDLALLELETSVVLNANTNPIDLAT- 141
            .|       ||...|      ..:|.:|..||...:...:|:.|:.:|.:|..:.|..||.|.:
  Fly   232 RTAVDCPPGGGSCSPEVQRLGFEEIRVHERYSEKASNQVHDIGLIRMERNVRYSDNIQPICLPSS 296

  Fly   142 ---ERPAAGSQIIFSGWGSSQVDGSLSHVLQVATRQSLSASDC-----QTELYLQQEDLLCLSPV 198
               |...:|.|...:|||.: :..:.|.|.|..|...:..:.|     |.::.|:...|......
  Fly   297 VGLESRQSGQQFTVAGWGRT-LKMARSAVKQKVTVNYVDPAKCRQRFSQIKVNLEPTQLCAGGQF 360

  Fly   199 DEDFAGLCSGDAGAP-ASYNNQ---LVGIAAFFVSGCG-SEQPDGYVDVTQHLEWINEN 252
            .:|   .|.||:|.| ..:.::   |.||.:|... || .:.|..|.:|..:..||.:|
  Fly   361 RKD---SCDGDSGGPLMRFRDESWVLEGIVSFGYK-CGLKDWPGVYTNVAAYDIWIRQN 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	68/252 (27%)
CG4653	NP_573150.2	Tryp_SPc	30..249	CDD:214473	66/249 (27%)
CG9733	NP_651784.2	CLIP	25..78	CDD:288855
		Tryp_SPc	161..412	CDD:214473	66/249 (27%)
		Tryp_SPc	162..415	CDD:238113	68/252 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457349
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930