DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4653 and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_573150.2	Gene:	CG4653 / 32650	FlyBaseID:	FBgn0030776	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001003979.1	Gene:	Tmprss11c / 408213	RGDID:	1302967	Length:	418	Species:	Rattus norvegicus

Alignment Length:	231	Identity:	69/231 - (29%)
Similarity:	109/231 - (47%)	Gaps:	21/231 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 AEVGSQPHSISLRRNGVHVCGGALIREKWILTAAHCVSLGGGQQSYPAKSYNVRVGSIQRLTGGQ 95
            ||.|..|...||::|.||.||..||...|::|||||.     .:|...|.:.|..|.:......|
  Rat   193 AEEGEWPWQASLQQNNVHRCGATLISNSWLITAAHCF-----VRSANPKDWKVSFGFLLSKPQAQ 252

  Fly    96 LVPLSKIIIHTNYSSSDAVGSNDLALLELETSVVLNANTNPIDL--ATERPAAGSQIIFSGWGSS 158
            .. :..|:||.|||.  ...:||:|::.|.:.|:...|.....|  ||::....|.::.:|||:.
  Rat   253 RA-VKSIVIHENYSY--PAHNNDIAVVRLSSPVLYENNIRRACLPEATQKFPPNSDVVVTGWGTL 314

  Fly   159 QVDGSLSHVLQVATRQSLSASDCQT-ELY--LQQEDLLCLSPVDEDFAGLCSGDAGAP-ASYNNQ 219
            :.||...::||....:.:....|.: :.|  :....:||...: |.....|.||:|.| .|.:::
  Rat   315 KSDGDSPNILQKGRVKIIDNKTCNSGKAYGGVITPGMLCAGFL-EGRVDACQGDSGGPLVSEDSK 378

  Fly   220 LVGIAAFFVSGCGSE-----QPDGYVDVTQHLEWIN 250
            .:...|..|| .|.|     :|..|..||.:.:||:
  Rat   379 GIWFLAGIVS-WGDECALPNKPGVYTRVTHYRDWIS 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	69/231 (30%)
CG4653	NP_573150.2	Tryp_SPc	30..249	CDD:214473	67/228 (29%)
Tmprss11c	NP_001003979.1	SEA	62..157	CDD:279699
		Tryp_SPc	186..412	CDD:214473	67/228 (29%)
		Tryp_SPc	187..415	CDD:238113	69/231 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920