Protein Alignment CG4653 and KLK3

DIOPT Version :10

• Sequence 1: NP_573150.2
• Gene: CG4653 / 32650
• FlyBaseID: FBgn0030776
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_001639.1
• Gene: KLK3 / 354
• HGNCID: 6364
• Length: 261
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 78/286 - (27%)
• Similarity: 113/286 - (39%)
• Gaps: 79/286 - (27%)

  Fly    16 VVIVTLGVVQSSRLP-----------AEVGSQPHSISLRRNGVHVCGGALIREKWILTAAHCVS- 68
            ||.:||.|......|           .|..|||..:.:...|..||||.|:..:|:||||||:.
Human     5 VVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRN 69

  Fly    69 -----LGGGQQSYPAKSYNVRVGSIQRLTGGQLVPLSKIIIHTNYSSS-----------DAVGSN 117
                 ||.....:|..:             ||:..:|....|..|..|           |:  |:
Human    70 KSVILLGRHSLFHPEDT-------------GQVFQVSHSFPHPLYDMSLLKNRFLRPGDDS--SH 119

  Fly   118 DLALLELETSVVLNANTNPIDLATERPAAGSQIIFSGWGSSQVDGSLS---------HVLQVATR 173
            ||.||.|.....|......:||.|:.||.|:....|||||.:.:..|:         ||:
Human   120 DLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVI----- 179

  Fly   174 QSLSASDCQTELYLQQ--EDLLCLSPVDEDFAG-------LCSGDAGAPASYNNQLVGIAAFFVS 229
                ::|...:::.|:  :.:||        ||       .||||:|.|...|..|.||.::...
Human   180 ----SNDVCAQVHPQKVTKFMLC--------AGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSE 232

  Fly   230 GCG-SEQPDGYVDVTQHLEWINENAV 254
            .|. .|:|..|..|..:.:||.:..|
Human   233 PCALPERPSLYTKVVHYRKWIKDTIV 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	72/268 (27%)
KLK3	NP_001639.1	Tryp_SPc	25..256	CDD:238113	71/262 (27%)