DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4653 and Prss53

DIOPT Version :9

Sequence 1:	NP_573150.2	Gene:	CG4653 / 32650	FlyBaseID:	FBgn0030776	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	290	Identity:	77/290 - (26%)
Similarity:	121/290 - (41%)	Gaps:	69/290 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QSYSHSRLLLLVVIVTLGVVQSSRL----------PAE----VGSQPHSISLRRNGVHVCGGALI 55
            ||:....|::..|:|..|:..:.|.          |.|    .|..|...|:||.|||:|.|:|:
Mouse     3 QSWRPELLIVGAVVVIEGLQAAQRACGQRGPGPPEPQEGNTLPGEWPWQASVRRQGVHICSGSLV 67

  Fly    56 REKWILTAAHCVSLGGGQQSYPAKSYNVRVGSIQ---RLTGGQLVPLSKIII---HTNYSSSDAV 114
            .:.|:||||||..   ...:....|::|.:||::   :..|.:.|.::.:.:   :.:||.
Mouse    68 ADTWVLTAAHCFE---KMATAELSSWSVVLGSLKQEGQSPGAEEVGVAALQLPKAYNHYSQ---- 125

  Fly   115 GSNDLALLELETSVVLNANTNP---IDLATERPA----AGSQIIFSGWGSSQVDGSLSHVLQVAT 172
             .:|||||:|         |:|   ..|...:|.    .|:....:||..:..|  :|..|:...
Mouse   126 -GSDLALLQL---------THPTVQTTLCLPQPTYHFPFGASCWATGWDQNTSD--VSRTLRNLR 178

  Fly   173 RQSLSASDCQTELY--LQQE--------DLLC--LSPVDEDFAGLCSGDAGAPASYNNQ-----L 220
            .:.:|...|.. ||  |.|.        .:||  ..|.::   |.|.||:|.|......     .
Mouse   179 LRLISRPTCNC-LYNRLHQRLLSNPARPGMLCGGAQPGEQ---GPCQGDSGGPVMCREPDGHWVQ 239

  Fly   221 VGIAAFFVSGCGSEQ-PDGYVDVTQHLEWI 249
            |||.: |.|.|..|. |....|:..|..|:
Mouse   240 VGIIS-FTSKCAQEDTPVLLTDMAVHSSWL 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	70/255 (27%)
CG4653	NP_573150.2	Tryp_SPc	30..249	CDD:214473	69/253 (27%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46		2/18 (11%)
		Tryp_SPc	45..271	CDD:238113	68/248 (27%)
		Tryp_SPc	311..522	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100