Protein Alignment CG4653 and Prss22

DIOPT Version :10

• Sequence 1: NP_573150.2
• Gene: CG4653 / 32650
• FlyBaseID: FBgn0030776
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_001100454.1
• Gene: Prss22 / 302971
• RGDID: 1310880
• Length: 307
• Species: Rattus norvegicus
• Alignment Length: 278
• Identity: 72/278 - (25%)
• Similarity: 120/278 - (43%)
• Gaps: 50/278 - (17%)

  Fly    12 LLLLVVIVTLGVVQSSRL--------PAE----VGSQ-------PHSISLRRNGVHVCGGALIRE 57
            |:|||::.:...|.::.:        |.:    ||.:       |..:|:.:||.|.|.|:|:..
  Rat    18 LILLVLLTSTATVSAANIRGSPDCGKPQQLNRVVGGEDSADAQWPWIVSILKNGSHHCAGSLLTN 82

  Fly    58 KWILTAAHCVSLGGGQQSYPAKSYNVRVGSIQRLTGG---QLVPLSKIIIHTNYSSSDAVGSNDL 119
            :|:::||||.|....:.|    .|:|.:|:.:....|   |.|.::.::.|..||..:...: |:
  Rat    83 RWVVSAAHCFSSNMDKPS----PYSVLLGAWKLGNPGPRSQKVGIASVLPHPRYSRKEGTHA-DI 142

  Fly   120 ALLELETSVVLNANTNPI---DLATERPAAGSQIIFSGWGSSQVDG---SLSHVLQVATRQSLSA 178
            ||:.||..:..:....||   |.:...| ..:....:||||.| ||   .....||......:..
  Rat   143 ALVRLERPIQFSERILPICLPDSSVHLP-PNTNCWIAGWGSIQ-DGVPLPRPQTLQKLKVPIIDP 205

  Fly   179 SDCQTELYLQ-------QEDLLCLSPVDEDFAGLCSGDAGAPASYNNQ----LVGIAAFFVSGCG 232
            ..|:: ||.:       .||:||...: |.....|.||:|.|......    |.||.: :..||.
  Rat   206 ELCKS-LYWRGAGQEAITEDMLCAGYL-EGKRDACLGDSGGPLMCQVDDHWLLTGIIS-WGEGCA 267

  Fly   233 S-EQPDGYVDVTQHLEWI 249
            . .:|..|..:..|..|:
  Rat   268 ERNRPGVYTSLLAHRPWV 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	67/252 (27%)
Prss22	NP_001100454.1	Tryp_SPc	50..288	CDD:238113	66/246 (27%)