Protein Alignment CG4653 and KLK13

DIOPT Version :10

• Sequence 1: NP_573150.2
• Gene: CG4653 / 32650
• FlyBaseID: FBgn0030776
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_056411.1
• Gene: KLK13 / 26085
• HGNCID: 6361
• Length: 277
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 82/268 - (30%)
• Similarity: 122/268 - (45%)
• Gaps: 39/268 - (14%)

  Fly    12 LLLLVVIVTL----GVVQSSR-----------LPAEVGSQPHS----ISLRRNGVHVCGGALIRE 57
            |.|::..:||    ||.|.|.           ||......|||    .:|...|..:|||.|:..
Human     4 LALVIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLLCGGVLVHP 68

  Fly    58 KWILTAAHCVSLGGGQQSYPAKSYNVRVGSIQRLTGGQLVPLSKIIIHTNY--SSSDAVGSNDLA 120
            ||:||||||  |..|.:.|..|.   .:|.::  .|.|:..:...|.|..|  |.:.....:|:.
Human    69 KWVLTAAHC--LKEGLKVYLGKH---ALGRVE--AGEQVREVVHSIPHPEYRRSPTHLNHDHDIM 126

  Fly   121 LLELETSVVLNANTNPIDLA-TERPAAGSQIIFSGWG---SSQVDGSLSHVLQVATRQSLSASDC 181
            ||||::.|.|......:.|: ..|...|:....||||   |.||  :....||.|..|..|..:|
Human   127 LLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQV--NYPKTLQCANIQLRSDEEC 189

  Fly   182 QTELYLQQ--EDLLCLSPVDEDFAGLCSGDAGAPASYNNQLVGIAAFFVSGCGS-EQPDGYVDVT 243
            : ::|..:  :::|| :...|.....|.||:|.|...|..|.||.::....||. ::|..|..|:
Human   190 R-QVYPGKITDNMLC-AGTKEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVS 252

  Fly   244 QHLEWINE 251
            :::.||.|
Human   253 RYVLWIRE 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	73/235 (31%)
KLK13	NP_056411.1	Tryp_SPc	38..261	CDD:238113	72/234 (31%)