Protein Alignment CG4653 and KLK5

DIOPT Version :10

• Sequence 1: NP_573150.2
• Gene: CG4653 / 32650
• FlyBaseID: FBgn0030776
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 75/244 - (30%)
• Similarity: 117/244 - (47%)
• Gaps: 38/244 - (15%)

  Fly    26 SSRL----PAEVGSQP--HSISLRRNGVHVCGGALIREKWILTAAHCVSLGGGQQSYPAKSYNVR 84
            |||:    ..::.:||  .::.||.|.:: ||..|:..:|:||||||          ..|.:.||
Human    64 SSRIINGSDCDMHTQPWQAALLLRPNQLY-CGAVLVHPQWLLTAAHC----------RKKVFRVR 117

  Fly    85 VG--SIQRL--TGGQLVPLSKIIIHTNYSSSDAVGSNDLALLELETSVVLNANTNPIDLATERPA 145
            :|  |:..:  :|.|:....|.|.|..||...  .||||.|::|...:....:..||::::..|:
Human   118 LGHYSLSPVYESGQQMFQGVKSIPHPGYSHPG--HSNDLMLIKLNRRIRPTKDVRPINVSSHCPS 180

  Fly   146 AGSQIIFSGWG---SSQVDGSLSHVLQVATRQSLSASDCQTELYLQQED--LLCLSPVDEDFAG- 204
            ||::.:.||||   |.||  ....|||......||...|: :.|.:|.|  :.|..    |.||
Human   181 AGTKCLVSGWGTTKSPQV--HFPKVLQCLNISVLSQKRCE-DAYPRQIDDTMFCAG----DKAGR 238

  Fly   205 -LCSGDAGAPASYNNQLVGIAAFFVSGCG-SEQPDGYVDVTQHLEWINE 251
             .|.||:|.|...|..|.|:.::....|. ..:|..|.::.:..:||.|
Human   239 DSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQE 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	72/236 (31%)
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		3/3 (100%)
		Tryp_SPc	66..285	CDD:214473	70/238 (29%)