Protein Alignment CG4653 and CTRL

DIOPT Version :10

• Sequence 1: NP_573150.2
• Gene: CG4653 / 32650
• FlyBaseID: FBgn0030776
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_001898.1
• Gene: CTRL / 1506
• HGNCID: 2524
• Length: 264
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 74/273 - (27%)
• Similarity: 124/273 - (45%)
• Gaps: 50/273 - (18%)

  Fly    12 LLLLVVIVTLGVVQSSRLP-----------------AEVGSQPHSISLR-RNGVHVCGGALIREK 58
            |.|.:.:|.||......:|                 |.:||.|..:||: .:|.|.|||:||.:.
Human     4 LSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQS 68

  Fly    59 WILTAAHC-VSLGGGQQSYPAKSYNVRVGSIQRLTGG---QLVPLSKIIIHTNYSSSDAVGSNDL 119
            |::||||| ||        |.:.: |.:|...|.:..   |::.:|:.|.|.:::|:..  :||:
Human    69 WVVTAAHCNVS--------PGRHF-VVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTM--NNDV 122

  Fly   120 ALLELETSVVLNANTNPIDLATERPA--AGSQIIFSGWGSSQVDGSL--SHVLQVATRQSLSASD 180
            .||:|.:........:|:.||:...|  .|...:.:|||.....|::  :|:.|||. ..::.:.
Human   123 TLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVAL-PLVTVNQ 186

  Fly   181 CQTELYLQQ---EDLLCLSPVDEDFAGLCSGDAGAP--ASYNNQ--LVGIAAFFVSGCGSEQPDG 238
            |:.  |...   :.::|.....   |..|.||:|.|  ....|.  |:||.::....|....|..
Human   187 CRQ--YWGSSITDSMICAGGAG---ASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCNVRAPAV 246

  Fly   239 YVDVTQHLEWINE 251
            |..|::...|||:
Human   247 YTRVSKFSTWINQ 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	69/255 (27%)
CTRL	NP_001898.1	Tryp_SPc	34..260	CDD:238113	68/243 (28%)