Protein Alignment CG4653 and PRSS36

DIOPT Version :10

• Sequence 1: NP_573150.2
• Gene: CG4653 / 32650
• FlyBaseID: FBgn0030776
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_775773.2
• Gene: PRSS36 / 146547
• HGNCID: 26906
• Length: 855
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 84/296 - (28%)
• Similarity: 121/296 - (40%)
• Gaps: 66/296 - (22%)

  Fly    12 LLLLVVIVTLGVVQSSRLP-------------------------AEVGSQPHSISLRRNGVHVCG 51
            |::||:....|..|.|.|.                         |:.|:.|..:||...|.|:||
Human     9 LVMLVISPIPGAFQDSALSPTQEEPEDLDCGRPEPSARIVGGSNAQPGTWPWQVSLHHGGGHICG 73

  Fly    52 GALIREKWILTAAHCVSLGGGQQSYPAKSYNVRVGSIQR---LTGGQLVPLSKIIIHTNYSSSDA 113
            |:||...|:|:||||....|..:  ||..::|.:|...:   |.|.....::.|::..|||..:
Human    74 GSLIAPSWVLSAAHCFMTNGTLE--PAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVE- 135

  Fly   114 VGSNDLALLELETSVVLNANTNPIDL--ATERPAAGSQIIFSGWGSSQVDG--SLSHVLQVATRQ 174
            :|: |||||.|.:...|.....|:.|  |:.|...|:....:|||..|...  .|..|||....:
Human   136 LGA-DLALLRLASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELR 199

  Fly   175 SLSASDCQTELYLQQ----------EDLLCLSPVDEDFAGLCSGDAGAPASYNNQLV-------- 221
            .|..:.||. ||.|.          ..:|| :...|.....|.||:|.|      ||
Human   200 LLGEATCQC-LYSQPGPFNLTLQILPGMLC-AGYPEGRRDTCQGDSGGP------LVCEEGGRWF 256

  Fly   222 --GIAAFFVSGCG-SEQPDGYVDVTQHLEWINENAV 254
              ||.:|.. ||| ..:|..:..|..:..||.|..:
Human   257 QAGITSFGF-GCGRRNRPGVFTAVATYEAWIREQVM 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	76/274 (28%)
PRSS36	NP_775773.2	Tryp_SPc	47..289	CDD:238113	76/254 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	292..316		84/296 (28%)
		Tryp_SPc	330..538	CDD:473915
		Tryp_SPc	601..783	CDD:473915