Protein Alignment CG4653 and Cfd

DIOPT Version :10

• Sequence 1: NP_573150.2
• Gene: CG4653 / 32650
• FlyBaseID: FBgn0030776
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_038487.1
• Gene: Cfd / 11537
• MGIID: 87931
• Length: 259
• Species: Mus musculus
• Alignment Length: 273
• Identity: 69/273 - (25%)
• Similarity: 113/273 - (41%)
• Gaps: 52/273 - (19%)

  Fly     9 HSRLLLLVVIVTLGVVQSSRLP---------AEVGSQPHSISLRRNGVHVCGGALIREKWILTAA 64
            ||. :..|.:|.||....:..|         |...::|:..|::.||.|||||.|:.|:|:|:||
Mouse     2 HSS-VYFVALVILGAAVCAAQPRGRILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAA 65

  Fly    65 HC-----------VSLGGGQQSYP---AKSYNVRVGSIQRLTGGQLVPLSKIIIHTNYSSSDAVG 115
            ||           |.||....|.|   .:.|:|:                .::.|.. |..|::
Mouse    66 HCMDGVTDDDSVQVLLGAHSLSAPEPYKRWYDVQ----------------SVVPHPG-SRPDSL- 112

  Fly   116 SNDLALLELETSVVLNANTNPIDLATE--RPAAGSQIIFSGWGSSQVDGSLSHVLQVATRQSLSA 178
            .:||.|.:|..:..|..:..|:.|..|  ....|:....:|||.....|....||.......::.
Mouse   113 EDDLILFKLSQNASLGPHVRPLPLQYEDKEVEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNR 177

  Fly   179 SDCQTELY---LQQEDLLCLSPVDEDFAGLCSGDAGAPASYNNQLVGIAAFFVSGCGS-EQPDGY 239
            :.|....|   :...:::|......|   .|.||:|:|....:.:.|:..:....||: ::|..|
Mouse   178 TTCNLRTYHDGVVTINMMCAESNRRD---TCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVY 239

  Fly   240 VDVTQHLEWINEN 252
            ..|:.:..|| ||
Mouse   240 TRVSSYRMWI-EN 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	61/250 (24%)
Cfd	NP_038487.1	Tryp_SPc	26..252	CDD:238113	62/248 (25%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		0/3 (0%)