Protein Alignment CG4653 and KLK8

DIOPT Version :10

• Sequence 1: NP_573150.2
• Gene: CG4653 / 32650
• FlyBaseID: FBgn0030776
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 73/253 - (28%)
• Similarity: 110/253 - (43%)
• Gaps: 39/253 - (15%)

  Fly    25 QSSRLPAEVG------------------SQPHSISLRRNGVHVCGGALIREKWILTAAHCVSLGG 71
            :|:.||...|                  |||...:|.:....:|||.|:...|:||||||
Human    60 RSNPLPPAAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHC----- 119

  Fly    72 GQQSYPAKSYNVRVG--SIQRLTG-GQLVPLSKIIIHTNYSSSDAVGSN-DLALLELETSVVLNA 132
                 ....|.||:|  |:|...| .|.:|:.:.|.|..|:|||....| ||.||:|.....|.:
Human   120 -----KKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGS 179

  Fly   133 NTNPIDLATERPAAGSQIIFSGWGS-SQVDGSLSHVLQVATRQSLSASDCQTELYLQQ--EDLLC 194
            ...||.||......|.:...||||: :....:....|..|..:......|: :.|..|  :.::|
Human   180 KVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCE-DAYPGQITDGMVC 243

  Fly   195 LSPVDEDFAGLCSGDAGAPASYNNQLVGIAAFFVSGCG-SEQPDGYVDVTQHLEWINE 251
            ..  ....|..|.||:|.|...:..|.||.::....|| |::|..|.::.::|:||.:
Human   244 AG--SSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	71/248 (29%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	67/232 (29%)