DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4653 and KLK11

DIOPT Version :9

Sequence 1:NP_573150.2 Gene:CG4653 / 32650 FlyBaseID:FBgn0030776 Length:254 Species:Drosophila melanogaster
Sequence 2:XP_011524671.1 Gene:KLK11 / 11012 HGNCID:6359 Length:307 Species:Homo sapiens


Alignment Length:276 Identity:75/276 - (27%)
Similarity:122/276 - (44%) Gaps:27/276 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 SPVQSYSHSRLLLLVVIVTLGVVQSSRL----PAEVGSQPHSISLRRNGVHVCGGALIREKWILT 62
            ||:|:....:|:||.:...| |...:|:    ..:..|||...:|......:||..||..:|:||
Human    28 SPLQAMRILQLILLALATGL-VGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLT 91

  Fly    63 AAHC----VSLGGGQQSYPAKS-----------YNVRVG--SIQRLTG-GQLVPLSKIIIHTNYS 109
            ||||    |||.......|..|           |.|.:|  ::|:..| .|....::...|..::
Human    92 AAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFN 156

  Fly   110 SS--DAVGSNDLALLELETSVVLNANTNPIDLATERPAAGSQIIFSGWGS-SQVDGSLSHVLQVA 171
            :|  :....||:.|:::.:.|.:.....|:.|::....||:..:.||||| |.....|.|.|:.|
Human   157 NSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCA 221

  Fly   172 TRQSLSASDCQTELYLQQEDLLCLSPVDEDFAGLCSGDAGAPASYNNQLVGIAAFFVSGCG-SEQ 235
            ....:....|:........|.:..:.|.|.....|.||:|.|...|..|.||.::....|. :.:
Human   222 NITIIEHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRK 286

  Fly   236 PDGYVDVTQHLEWINE 251
            |..|..|.::::||.|
Human   287 PGVYTKVCKYVDWIQE 302

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4653NP_573150.2 Tryp_SPc 30..252 CDD:238113 66/244 (27%)
Tryp_SPc 30..249 CDD:214473 63/240 (26%)
KLK11XP_011524671.1 Tryp_SPc 53..300 CDD:214473 64/246 (26%)
Tryp_SPc 54..303 CDD:238113 66/249 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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