DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9673 and Tmprss9

DIOPT Version :9

Sequence 1:	NP_001285346.1	Gene:	CG9673 / 32649	FlyBaseID:	FBgn0030775	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	XP_006513905.2	Gene:	Tmprss9 / 432478	MGIID:	3612246	Length:	1342	Species:	Mus musculus

Alignment Length:	263	Identity:	77/263 - (29%)
Similarity:	120/263 - (45%)	Gaps:	41/263 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 SAEASPQ-----------GRILGGEDVAQGEYPWSASVRYNKAHVCSGAIISTNHILTAAHCVSS 73
            |..|.||           .||:||.....||.||.||::....|.|...::....:|:||||.:.
Mouse   737 STTAKPQECGARPAMDKPTRIVGGISAVSGEVPWQASLKEGPRHFCGATVVGDRWLLSAAHCFNH 801

  Fly    74 VGITPVDASTLAVRLGTINQY-AGGSIV--NVKSVIIHPSY--GNFLHDIAILELDETLVFSDRI 133
            ..:..|.|     .|||::.. .|||.|  .::.|.:||.|  |....|:|:|||.:.|||:..|
Mouse   802 TKVEQVQA-----HLGTVSLLGVGGSPVKLGLRRVALHPRYNPGILDFDVALLELAQPLVFNKYI 861

  Fly   134 QDIALPPTTDEETEDVDAELPNGTPVYVAGWGELSDGTASYKQ--QKANYNTLSRSLCEWEAGYG 196
            |.:.||....        :.|.|....::|||.:.:|.|:...  |||:...:.:.:|  .|.|.
Mouse   862 QPVCLPLAIH--------KFPVGRKCMISGWGNMQEGNATKPDILQKASVGIIEQKMC--GALYN 916

  Fly   197 Y---ESVVCLSRAEGE-GICRGDAGAAVIDDDK----VLRGLTSFNFGPCGSKYPDVATRVSYYL 253
            :   :.::|....||. ..|:||:|..:..::.    .|.|:.|:..|...:|.|.|..|::...
Mouse   917 FSLTDRMLCAGFLEGRVDSCQGDSGGPLACEETPGVFYLAGIVSWGIGCAQAKKPGVYARITRLK 981

  Fly   254 TWI 256
            .||
Mouse   982 DWI 984

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9673	NP_001285346.1	Tryp_SPc	28..256	CDD:214473	71/242 (29%)
CG9673	NP_001285346.1	Tryp_SPc	29..259	CDD:238113	72/243 (30%)
Tmprss9	XP_006513905.2	SEA	285..365	CDD:366610
		LDLa	407..442	CDD:238060
		Tryp_SPc	455..684	CDD:214473
		Tryp_SPc	756..984	CDD:214473	71/242 (29%)
		Tryp_SPc	1085..1336	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BGUI
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810