DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9673 and Tmprss4

DIOPT Version :9

Sequence 1:	NP_001285346.1	Gene:	CG9673 / 32649	FlyBaseID:	FBgn0030775	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	XP_038937788.1	Gene:	Tmprss4 / 367074	RGDID:	1305033	Length:	478	Species:	Rattus norvegicus

Alignment Length:	243	Identity:	81/243 - (33%)
Similarity:	122/243 - (50%)	Gaps:	31/243 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 RILGGEDVAQGEYPWSASVRYNKAHVCSGAIISTNHILTAAHCVSSVGITPVDASTLAVRLGTIN 92
            |::||.:.:...:||..|::|||.|||.|:|:..:.|||||||....    :|.|:..||.|:..
  Rat   245 RVVGGVEASADSWPWQVSIQYNKQHVCGGSILDHHWILTAAHCFRKY----LDVSSWKVRAGSNK 305

  Fly    93 QYAGGSIVNVKSVIIHPSYGNFLH----DIAILELDETLVFSDRIQDIALPPTTDEETEDVDAEL 153
            .....|:...|..|..|   |.|.    |||:::|...|.||..::.|.||.:        |.||
  Rat   306 LGNSPSLPVAKIFIAEP---NPLQPKEKDIALVKLKMPLTFSGSVRPICLPFS--------DEEL 359

  Fly   154 PNGTPVYVAGWG--ELSDGTASYKQQKANYNTLSRSLCEWEAGYGYE---SVVCLSRAE-GEGIC 212
            ....||:|.|||  |.:.|..|....:|:...:..:.|..|..|..|   .::|....: |:..|
  Rat   360 IPTMPVWVIGWGFTEENGGKMSDTLLQASVQVIDSARCNAEDAYQGEVTAGMLCAGTPQGGKDTC 424

  Fly   213 RGDAGAAVI---DDDKVLRGLTSFNFGPCGS-KYPDVATRVSYYLTWI 256
            :||:|..::   |..:|: |:.|:.:| ||| ..|.|.|:|:.||.||
  Rat   425 QGDSGGPLMYHYDKWQVV-GIVSWGYG-CGSPSTPGVYTKVTAYLDWI 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9673	NP_001285346.1	Tryp_SPc	28..256	CDD:214473	79/241 (33%)
CG9673	NP_001285346.1	Tryp_SPc	29..259	CDD:238113	80/242 (33%)
Tmprss4	XP_038937788.1	LDLa	99..133	CDD:238060
		SRCR_2	149..238	CDD:413346
		Tryp_SPc	245..470	CDD:214473	79/241 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341279
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840