DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9673 and Tmprss4

DIOPT Version :9

Sequence 1:	NP_001285346.1	Gene:	CG9673 / 32649	FlyBaseID:	FBgn0030775	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_663378.1	Gene:	Tmprss4 / 214523	MGIID:	2384877	Length:	435	Species:	Mus musculus

Alignment Length:	240	Identity:	77/240 - (32%)
Similarity:	117/240 - (48%)	Gaps:	25/240 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 RILGGEDVAQGEYPWSASVRYNKAHVCSGAIISTNHILTAAHCVSSVGITPVDASTLAVRLGTIN 92
            |::||.:.....:||..|::|||.|||.|:|:..:.|||||||....    :|.|:..||.|: |
Mouse   202 RVVGGVEAPVDSWPWQVSIQYNKQHVCGGSILDPHWILTAAHCFRKY----LDVSSWKVRAGS-N 261

  Fly    93 QYAGGSIVNVKSVII---HPSYGNFLHDIAILELDETLVFSDRIQDIALPPTTDEETEDVDAELP 154
            .......:.|..:.|   :|.|.. ..|||:::|...|.||..::.|.||.:        |..|.
Mouse   262 ILGNSPSLPVAKIFIAEPNPLYPK-EKDIALVKLQMPLTFSGSVRPICLPFS--------DEVLV 317

  Fly   155 NGTPVYVAGWG--ELSDGTASYKQQKANYNTLSRSLCEWEAGYGYE---SVVCLSRAE-GEGICR 213
            ..|||:|.|||  |.:.|..|....:|:...:..:.|..|..|..|   .::|....: |:..|:
Mouse   318 PATPVWVIGWGFTEENGGKMSDMLLQASVQVIDSTRCNAEDAYEGEVTAEMLCAGTPQGGKDTCQ 382

  Fly   214 GDAGAAVI--DDDKVLRGLTSFNFGPCGSKYPDVATRVSYYLTWI 256
            ||:|..::  .|...:.|:.|:..|..|...|.|.|:|:.||.||
Mouse   383 GDSGGPLMYHSDKWQVVGIVSWGHGCGGPSTPGVYTKVTAYLNWI 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9673	NP_001285346.1	Tryp_SPc	28..256	CDD:214473	75/238 (32%)
CG9673	NP_001285346.1	Tryp_SPc	29..259	CDD:238113	76/239 (32%)
Tmprss4	NP_663378.1	LDLa	56..90	CDD:238060
		SRCR_2	106..195	CDD:295335
		Tryp_SPc	202..427	CDD:214473	75/238 (32%)
		Tryp_SPc	203..430	CDD:238113	76/239 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837546
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840