Protein Alignment sphe and TMPRSS13

DIOPT Version :10

• Sequence 1: NP_573148.2
• Gene: sphe / 32648
• FlyBaseID: FBgn0030774
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_001070731.1
• Gene: TMPRSS13 / 84000
• HGNCID: 29808
• Length: 567
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 60/246 - (24%)
• Similarity: 117/246 - (47%)
• Gaps: 20/246 - (8%)

  Fly    18 GMCHAQGRIMGGEDADATATTFTASLRVDNAHVCGGSILSQTKILTTAHC--VHRDGKLIDASRL 80
            |:....|||:||..|..:...:..||.....|:|||:::....:||.|||  |.|: |:::..::
Human   318 GLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTRE-KVLEGWKV 381

  Fly    81 ACRVGSTNQYAGGKIVNVESVAVHPDYYNLNN--NLAVITLSSELTYTDRITAIPLVASGEALPA 143
              ..|::|.:...:..::..:.::.:|.:..:  ::|::.||..||.:..|....|...|:.. :
Human   382 --YAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTF-S 443

  Fly   144 EGSEVIVAGWGRT--SDGTNSYKIRQISLKVAPEATCLD--AYSDHDEQSFCLAHELKEG--TCH 202
            ......:.|:|:|  :|...|..:|::.:.:.....|.|  .|..:.......|.:|:.|  :|.
Human   444 LNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQ 508

  Fly   203 GDGGGGAIYGNT----LIGLTNFVVGACGSR-YPDVFVRLSSYADWIQEQI 248
            ||.||..:....    |.|:|::..| ||.| .|.|:.:::....||..::
Human   509 GDSGGPLVCEQNNRWYLAGVTSWGTG-CGQRNKPGVYTKVTEVLPWIYSKM 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	53/219 (24%)
TMPRSS13	NP_001070731.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..115
		PHA03378	<9..148	CDD:223065
		13 X 5 AA repeats of A-S-P-A-[GLQR]	9..93
		4 X 5 AA repeats of T-P-P-G-R	14..68
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	131..157
		SRCR_2	231..321	CDD:464747	1/2 (50%)
		Tryp_SPc	325..554	CDD:214473	56/233 (24%)