Protein Alignment sphe and PRSS27

DIOPT Version :10

• Sequence 1: NP_573148.2
• Gene: sphe / 32648
• FlyBaseID: FBgn0030774
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_114154.1
• Gene: PRSS27 / 83886
• HGNCID: 15475
• Length: 290
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 67/284 - (23%)
• Similarity: 125/284 - (44%)
• Gaps: 44/284 - (15%)

  Fly     1 MMQPRLVILGLI---------GLTAVGMCHAQGRIMGGEDADATATTFTASLRVDNAHVCGGSIL 56
            |.:|..|.|.|:         ..||.|......|::||:|.......:..|::.:.:|.||||::
Human     1 MRRPAAVPLLLLLCFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLI 65

  Fly    57 SQTKILTTAHCVHRDGK------LIDASRLACRVGSTNQYAGGKIVNVESVAVHPDYYNL--NNN 113
            ::..:||.|||.....:      |:.|.:|. :.|....||  ::..|||   :|.|...  :.:
Human    66 AEQWVLTAAHCFRNTSETSLYQVLLGARQLV-QPGPHAMYA--RVRQVES---NPLYQGTASSAD 124

  Fly   114 LAVITLSSELTYTDRITAIPLVASGEALPAE-GSEVIVAGWGRTSDG---TNSYKIRQISLKVAP 174
            :|::.|.:.:.:|:.|  :|:.....::..| |....|.|||..|:.   .....::::::.:..
Human   125 VALVELEAPVPFTNYI--LPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIID 187

  Fly   175 EATCLDAYSDHDEQSF----------CLA-HELKEGTCHGDGGGG--AIYGNTLI--GLTNFVVG 224
            ...|...||...|..:          |.. .|.|:..|.||.||.  .:.|.:.:  |:.::..|
Human   188 TPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEG 252

  Fly   225 ACGSRYPDVFVRLSSYADWIQEQI 248
            ......|.|::|::::.:||...|
Human   253 CARQNRPGVYIRVTAHHNWIHRII 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	54/231 (23%)
PRSS27	NP_114154.1	Tryp_SPc	36..275	CDD:238113	57/246 (23%)