DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sphe and CG18754

DIOPT Version :9

Sequence 1:	NP_573148.2	Gene:	sphe / 32648	FlyBaseID:	FBgn0030774	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	260	Identity:	55/260 - (21%)
Similarity:	99/260 - (38%)	Gaps:	59/260 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 RIMGGEDADATATTFTASLRVDN-----------AHVCGGSILSQTKIL--------TTAHCVHR 70
            |..|.|:|:.....:...|..:|           ||...|..|:|..::        :|..|:..
  Fly   105 RDRGAENAELNEYPWMVLLLYENRLSLIRYVLTAAHCVIGGYLTQNDLVLKSVRLGESTTDCITS 169

  Fly    71 DGKLIDASRLACRVGSTNQY-----AGGKIVNVESVAVHPDYYNLNNNLAVITLSSELTYTDRIT 130
            :.:   ...|...||.|..:     :||               ...|::|::.|...:.||.:|.
  Fly   170 ESR---CPHLDVEVGQTTVHQGFTSSGG---------------TYRNDIALLRLQFPVRYTKKIQ 216

  Fly   131 AIPLVASGEALPAEGSEVIVAGWGRTSDGTNSYKIRQISLKVAPEATCLDAY-SDHDEQSFCLAH 194
            .|.|:.:  ..|.:...:.::||..|.   :|..:...::|....|.||:.| |.......|...
  Fly   217 PICLLDA--EFPLQDLNLQISGWDPTK---SSQTLITSTVKERNPADCLNRYPSFRSASQVCAGG 276

  Fly   195 ELKEGTCHGDGGGGAIYGNTLIGLTNFV----VGACGSRY------PDVFVRLSSYADWIQEQIA 249
            :.|..||.|. .|..:.|....|:..||    :.:.|.:|      |.|:.::..:::||:..:|
  Fly   277 QRKGDTCAGI-SGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIKANLA 340

Fly 250 249
Fly 341 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	50/239 (21%)
sphe	NP_573148.2	Tryp_SPc	42..244	CDD:214473	48/236 (20%)
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	53/253 (21%)
		Tryp_SPc	108..335	CDD:214473	51/250 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436515
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930