Protein Alignment sphe and KLK10

DIOPT Version :9

• Sequence 1: NP_573148.2
• Gene: sphe / 32648
• FlyBaseID: FBgn0030774
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_001070968.1
• Gene: KLK10 / 5655
• HGNCID: 6358
• Length: 276
• Species: Homo sapiens
• Alignment Length: 218
• Identity: 52/218 - (23%)
• Similarity: 88/218 - (40%)
• Gaps: 35/218 - (16%)

  Fly    51 CGGSILSQTKILTTAHCVHRDGKLIDASRLACRVGSTN--QYAGGKIVNVESVAVHPDYYNLN-- 111
            |.|.::.|:.:||.|||.::.        |..|||..:  ...|.::.......|||.|:..:
Human    71 CAGVLVDQSWVLTAAHCGNKP--------LWARVGDDHLLLLQGEQLRRTTRSVVHPKYHQGSGP 127

  Fly   112 --------NNLAVITLSSELTYTDRITAIPLVASGEALP----AEGSEVIVAGWGRTSDGTNSYK 164
                    ::|.::.|:..:....|:.|:       .||    ..|.:..|||||.|:.....|.
Human   128 ILPRRTDEHDLMLLKLARPVVLGPRVRAL-------QLPYRCAQPGDQCQVAGWGTTAARRVKYN 185

  Fly   165 --IRQISLKVAPEATCLDAYSD-HDEQSFCLAHELKEGTCHGDGGGGAIYGNTLIGLTNFVVGAC 226
              :...|:.:.....|...|.. ......|...:..:..|..|.||..:...||.|:.::.|..|
Human   186 KGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQSDSGGPLVCDETLQGILSWGVYPC 250

  Fly   227 GS-RYPDVFVRLSSYADWIQEQI 248
            || ::|.|:.::..|..||.:.|
Human   251 GSAQHPAVYTQICKYMSWINKVI 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	51/215 (24%)
		Tryp_SPc	42..244	CDD:214473	49/212 (23%)
KLK10	NP_001070968.1	Tryp_SPc	49..272	CDD:238113	51/215 (24%)
		Tryp_SPc	49..269	CDD:214473	49/212 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920