Protein Alignment sphe and KLK7

DIOPT Version :10

• Sequence 1: NP_573148.2
• Gene: sphe / 32648
• FlyBaseID: FBgn0030774
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 64/260 - (24%)
• Similarity: 111/260 - (42%)
• Gaps: 31/260 - (11%)

  Fly     1 MMQPRLVILGLIGLTAVGMCHAQG-RIMGGEDADATATTFTASLRVDNAHVCGGSILSQTKILTT 64
            ::.|..::|..:.|...|. .||| :|:.|......:..:..:|...|...|||.::::..:||.
Human     5 LLLPLQILLLSLALETAGE-EAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68

  Fly    65 AHC------VHRDGKLIDASRLACRVGSTNQYAGGKIVNVESVAVHPDYYNLN--NNLAVITLSS 121
            |||      ||.....: ..|.|.|:.::..:.            ||.|....  |:|.::.|:|
Human    69 AHCKMNEYTVHLGSDTL-GDRRAQRIKASKSFR------------HPGYSTQTHVNDLMLVKLNS 120

  Fly   122 ELTYTDRITAIPLVASGEALPAEGSEVIVAGWGRTS--DGTNSYKIRQISLKVAPEATCLDAYSD 184
            :...:..:..:.|.:..|   ..|:...|:|||.|:  |.|....:..:.:|:.....|...|.|
Human   121 QARLSSMVKKVRLPSRCE---PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD 182

  Fly   185 HDEQSFCLA--HELKEGTCHGDGGGGAIYGNTLIGLTNFVVGACGS-RYPDVFVRLSSYADWIQE 246
            ..|.|...|  .:.|:..|:||.||..:...||.||.::....||. ..|.|:.::..:..||.:
Human   183 LLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIND 247

  Fly   247  246
            Human   248  247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	55/218 (25%)
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	55/231 (24%)