Protein Alignment sphe and Prss53

DIOPT Version :10

• Sequence 1: NP_573148.2
• Gene: sphe / 32648
• FlyBaseID: FBgn0030774
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: XP_006230384.1
• Gene: Prss53 / 499270
• RGDID: 1566127
• Length: 591
• Species: Rattus norvegicus
• Alignment Length: 325
• Identity: 68/325 - (20%)
• Similarity: 122/325 - (37%)
• Gaps: 100/325 - (30%)

  Fly     4 PRLVILGLI----GLTAVGMCHAQ----------GRIMGGEDADATATTFTASLRVDNAHVCGGS 54
            |.|:|:|.:    ||.|......|          |..:.||      ..:.||:|....|:|.||
  Rat     7 PELLIVGAVIVIEGLQAAQRACGQRGPGPPEPQEGNTLPGE------WPWQASVRRQGVHICSGS 65

  Fly    55 ILSQTKILTTAHCVHRDGKLIDASRLACRVGSTNQYA---GGKIVNVESVAVHPDY--YNLNNNL 114
            :::.|.:||.|||..:.. ..:.|..:..:||..|..   |.:.|.|.::.:...|  |:..::|
  Rat    66 LVADTWVLTAAHCFEKMA-TAELSSWSVVLGSLKQEGLSPGAEEVGVAALQLPKAYNHYSQGSDL 129

  Fly   115 AVITLSSELTYTDRITAIPLVASGEALPAE------GSEVIVAGWGR-TSDGTN----------- 161
            |::    :||:       |:|.:...||..      |:.....||.: ||||..
  Rat   130 ALL----QLTH-------PIVHTTLCLPQPTHHFPFGASCWATGWDQNTSDGKYCPRHKSRESQT 183

  Fly   162 --------------------------SYKIRQISLKVAPEATCLDAYSDHDEQSFCLAHELK--- 197
                                      |..:|.:.|::....||...|:...::  .||:..:
  Rat   184 GSVLTVLALCSHCVSELDSTLSPLPVSRTLRNLRLRLISRPTCNCLYNRLHQR--LLANPARSGM 246

  Fly   198 ---------EGTCHGDGGGGAIY----GNTL-IGLTNFVVGACGSRYPDVFVRLSSYADWIQEQI 248
                     :|.|.||.||..:.    |:.: :|:.:|.........|.:...:::::.|:|..:
  Rat   247 LCGGAQPGVQGPCQGDSGGPVMCREPDGHWVQVGIISFTSNCAQEDTPVLLTDMAAHSSWLQAHV 311

  Fly   249  248
              Rat   312  311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	56/270 (21%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113	59/284 (21%)
		Tryp_SPc	341..561	CDD:238113