DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sphe and SPE

DIOPT Version :9

Sequence 1:	NP_573148.2	Gene:	sphe / 32648	FlyBaseID:	FBgn0030774	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_651168.1	Gene:	SPE / 42791	FlyBaseID:	FBgn0039102	Length:	400	Species:	Drosophila melanogaster

Alignment Length:	247	Identity:	62/247 - (25%)
Similarity:	106/247 - (42%)	Gaps:	63/247 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 CGGSILSQTKILTTAHC-----VHRDGKLIDASRLA---------CRVGSTNQYAGGKI------ 95
            |||::|:...:||..||     :.:.|.::.:.||.         |    |.|..|.:|
  Fly   166 CGGALLNSRYVLTAGHCLASRELDKSGAVLHSVRLGEWDTRTDPDC----TTQMNGQRICAPKHI 226

  Fly    96 -VNVESVAVH----PDYYNLNNNLAVITLSSELTYTDRITAIPLVASGEALPAEG--------SE 147
             :.||...:|    |:..:..|::|::.|...::|||.:..|       .||.:|        ..
  Fly   227 DIEVEKGIIHEMYAPNSVDQRNDIALVRLKRIVSYTDYVRPI-------CLPTDGLVQNNFVDYG 284

  Fly   148 VIVAGWGRTSDGTNSYKIRQISLKVAPEATCLDAYSDH----DEQSFCLAHELKEGTCHGDGGG- 207
            :.|||||.|.:...|....:|::.|....:|.:.||..    |:...|...:|...||.||.||
  Fly   285 MDVAGWGLTENMQPSAIKLKITVNVWNLTSCQEKYSSFKVKLDDSQMCAGGQLGVDTCGGDSGGP 349

  Fly   208 ----------GAIYGNTLIGLTNFVVGACGSR-YPDVFVRLSSYADWIQEQI 248
                      ...|   :.|:|::....||.: :|.|:.|..::.|||::::
  Fly   350 LMVPISTGGRDVFY---IAGVTSYGTKPCGLKGWPGVYTRTGAFIDWIKQKL 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	62/244 (25%)
sphe	NP_573148.2	Tryp_SPc	42..244	CDD:214473	60/241 (25%)
SPE	NP_651168.1	CLIP	42..94	CDD:314844
SPE	NP_651168.1	Tryp_SPc	135..397	CDD:238113	62/244 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436524
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930