DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sphe and CG16710

DIOPT Version :9

Sequence 1:	NP_573148.2	Gene:	sphe / 32648	FlyBaseID:	FBgn0030774	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_651167.3	Gene:	CG16710 / 42790	FlyBaseID:	FBgn0039101	Length:	372	Species:	Drosophila melanogaster

Alignment Length:	269	Identity:	62/269 - (23%)
Similarity:	108/269 - (40%)	Gaps:	60/269 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 RIMGGEDADATATTFTA-------SLRVDNAHV---CGGSILSQTKILTTAHCVHRDGKLIDASR 79
            ||.|||:.......:.|       |..|.|..:   |.||:::...:||.|||:...|  :|..|
  Fly   105 RIFGGEETQPNELPWMALILYAHRSRSVWNERLVSRCAGSLITNRYVLTAAHCLRITG--LDLRR 167

  Fly    80 LACRVGSTNQYAGGKIVNVESVAVH--PDYYNLN------------------NNLAVITLSSELT 124
            :  |:|..|..:....|...:...|  |::..::                  |::|::.|...:.
  Fly   168 V--RLGEHNILSNPDCVTHINGREHCAPEHLEIDVDLSIKHRHYMVFEERPYNDIALLRLKFPVR 230

  Fly   125 YTDRITAI----PLVASGEALPAEGSEVIVAGWGRTSDGTNSYKIRQ--ISLKVAPEATCLDAYS 183
            ||.:|..|    ..:.|..:.  ...::.:||||.:.....|..:.|  ::.:.|.|.:..:...
  Fly   231 YTAQIKPICVQLDYIFSNPSF--SNHKLQIAGWGLSHKQGYSNVLLQAYVNGRNADECSLSEPSL 293

  Fly   184 DHDEQSFCLAHEL-KEGTCHGDGGGGA-----------IYGNTLIGLTNFVVGACGSRY-PDVFV 235
            ..|:::...|..| ...||.||.||..           :|   |.|:|::....||  | |..:.
  Fly   294 GLDKETHICAGNLGGNDTCKGDSGGPLMAIMERGDEEFVY---LAGITSYGYSQCG--YGPAAYT 353

  Fly   236 RLSSYADWI 244
            :.|.:.:||
  Fly   354 KTSKFVEWI 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	56/245 (23%)
sphe	NP_573148.2	Tryp_SPc	42..244	CDD:214473	54/243 (22%)
CG16710	NP_651167.3	CLIP	35..84	CDD:288855
		Tryp_SPc	105..362	CDD:214473	60/267 (22%)
		Tryp_SPc	106..362	CDD:238113	59/266 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436518
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930