DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sphe and CG31326

DIOPT Version :9

Sequence 1:	NP_573148.2	Gene:	sphe / 32648	FlyBaseID:	FBgn0030774	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_650344.2	Gene:	CG31326 / 41728	FlyBaseID:	FBgn0051326	Length:	520	Species:	Drosophila melanogaster

Alignment Length:	223	Identity:	61/223 - (27%)
Similarity:	106/223 - (47%)	Gaps:	27/223 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 AHVCGGSILSQTKILTTAHCVHRDGKLIDASRLACRVGSTNQ--YAGGKIVNVESVAVHPDY--- 107
            |.:|||:::|.:.:|:.|||....|:.:.|||||..:|....  ::.|:...|..:.:|.::
  Fly   301 AFICGGTLISTSTVLSAAHCFRAPGRDLPASRLAVSLGRNTLAIHSDGEFRGVSQLIIHENFQFK 365

  Fly   108 YNLNNNLAVITLSSELTYTDRITAIPLVASGEA--LPAEGSEVIVAGWGRTSDGTNSYKIRQIS- 169
            .....:||::.|...:.|||.|..|.|.::...  || :|.:..|||||....||.:.::.:::
  Fly   366 QFTEADLALVRLDEPVRYTDYIVPICLWSTSNRMDLP-QGLKSYVAGWGPDETGTGNTEVSKVTD 429

  Fly   170 LKVAPEATC-LDAYSDHDEQSFCLAHELKEGTCHGDGGG-------------GAIYGNTLIGLTN 220
            |.:..||.| |:......:.|...|.:...|.|..||||             |.|.|    |:.|
  Fly   430 LNIVSEANCALELPHVLVQPSSLCAKKTGAGPCASDGGGPLMLREQDVWVLRGVISG----GVIN 490

  Fly   221 FVVGACGSRYPDVFVRLSSYADWIQEQI 248
            .....|....|.||..::.:.:|:::::
  Fly   491 EKENTCELSKPSVFTDVAKHIEWVRQKM 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	61/220 (28%)
sphe	NP_573148.2	Tryp_SPc	42..244	CDD:214473	60/217 (28%)
CG31326	NP_650344.2	GD_N	26..126	CDD:292649
		Tryp_SPc	277..517	CDD:238113	61/220 (28%)
		Tryp_SPc	277..514	CDD:214473	60/217 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471161
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930