DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sphe and MP1

DIOPT Version :9

Sequence 1:	NP_573148.2	Gene:	sphe / 32648	FlyBaseID:	FBgn0030774	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_001303421.1	Gene:	MP1 / 40541	FlyBaseID:	FBgn0027930	Length:	400	Species:	Drosophila melanogaster

Alignment Length:	267	Identity:	69/267 - (25%)
Similarity:	117/267 - (43%)	Gaps:	48/267 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 RIMGGEDADATATTFTASLRVD-----NAHVCGGSILSQTKILTTAHCVH-----------RDGK 73
            |::||.:.......:.|.:...     ..|.||||:::...:||.||||.           |.|:
  Fly   137 RVVGGNETTKREFPWMALIEYTKPGNVKGHHCGGSLINHRYVLTAAHCVSAIPSDWELTGVRLGE 201

  Fly    74 LIDASRLACRVGSTNQYAGGKIVN-------VESVAVHPDYYNLN----NNLAVITLSSELTYTD 127
            ...::...|.||..    |.:..|       ||....||.|...:    |::|::.|..|:.|:|
  Fly   202 WDASTNPDCTVGKN----GRRDCNEPYVDYPVEERIPHPQYPGNSRDQLNDIALLRLRDEVQYSD 262

  Fly   128 RI--TAIPLVASGEALPAEGSEVIVAGWGRT-SDGTNSYKIRQISLKVAPEATCLDAYSDH---- 185
            .|  ..:|.:||.......|.:|:||||||| ::.|::.|:: ..|...|.:.|...|:..
  Fly   263 FILPVCLPTLASQHNNIFLGRKVVVAGWGRTETNFTSNIKLK-AELDTVPTSECNQRYATQRRTV 326

  Fly   186 DEQSFCLAHELKEGTCHGDGGGGAIY-----GNT---LIGLTNFVVGACGSR-YPDVFVRLSSYA 241
            ..:..|........:|.||.||..:.     ||:   :.|:.::....||.: :|.|:.|:.:|.
  Fly   327 TTKQMCAGGVEGVDSCRGDSGGPLLLEDYSNGNSNYYIAGVVSYGPTPCGLKGWPGVYTRVEAYL 391

  Fly   242 DWIQEQI 248
            :||:..:
  Fly   392 NWIENNV 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	65/247 (26%)
sphe	NP_573148.2	Tryp_SPc	42..244	CDD:214473	63/244 (26%)
MP1	NP_001303421.1	CLIP	29..91	CDD:288855
		Tryp_SPc	137..394	CDD:214473	67/261 (26%)
		Tryp_SPc	138..397	CDD:238113	68/263 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436523
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840