Protein Alignment sphe and PRSS38

DIOPT Version :10

• Sequence 1: NP_573148.2
• Gene: sphe / 32648
• FlyBaseID: FBgn0030774
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_898885.1
• Gene: PRSS38 / 339501
• HGNCID: 29625
• Length: 326
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 69/266 - (25%)
• Similarity: 118/266 - (44%)
• Gaps: 30/266 - (11%)

  Fly     3 QPRLVILGLIGLTAVGMCHAQGRIMGGEDADATATTFTASLRVDNAHVCGGSILSQTKILTTAHC 67
            ||....:.|.|..|.|....:|:|:||..|......:..|:.....||||||||::..:|:.|||
Human    37 QPENQGISLTGSVACGRPSMEGKILGGVPAPERKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHC 101

  Fly    68 VHRDG--KLIDASRLACRVGSTNQYAGG---KIVNVESVAVHPD---YYNLNNNLAVITLSSELT 124
            .|||.  |:.|     ..||..|....|   :...|..|.:||.   |:.:..::|::.|.:.:.
Human   102 FHRDKNIKIYD-----MYVGLVNLRVAGNHTQWYEVNRVILHPTYEMYHPIGGDVALVQLKTRIV 161

  Fly   125 YTDRITAIPLVASGEALPAEGSEVIVAGWGRTS-DGTNSYKIRQISLKVAPEATCLDAYSDHDEQ 188
            :::.:  :|:..:...:....:.....|||..| .|..|.:::::.|.:..|..|...|.   ..
Human   162 FSESV--LPVCLATPEVNLTSANCWATGWGLVSKQGETSDELQEMQLPLILEPWCHLLYG---HM 221

  Fly   189 SFCLAHELKEG-------TCHGDGGGGAI--YGNT--LIGLTNFVVGACGSRYPDVFVRLSSYAD 242
            |:.:...|..|       .|.||.||..:  :..:  .||:.::..|.....||.|:..:|.::.
Human   222 SYIMPDMLCAGDILNAKTVCEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSK 286

  Fly   243 WIQEQI 248
            ||.:.|
Human   287 WICDNI 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	57/224 (25%)
PRSS38	NP_898885.1	Tryp_SPc	60..291	CDD:238113	61/240 (25%)