DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sphe and spirit

DIOPT Version :9

Sequence 1:	NP_573148.2	Gene:	sphe / 32648	FlyBaseID:	FBgn0030774	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_001162707.1	Gene:	spirit / 31797	FlyBaseID:	FBgn0030051	Length:	393	Species:	Drosophila melanogaster

Alignment Length:	218	Identity:	59/218 - (27%)
Similarity:	92/218 - (42%)	Gaps:	41/218 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 CGGSILSQTKILTTAHCVHRDGKLIDASRLACRVGSTNQYAGGKIVNVESVAVHPDYYNLNNNLA 115
            |||::::...:||.|||....|:.....||.   |.......|:.:::..|.:||||
  Fly   163 CGGALIANNFVLTAAHCADLGGEPPSQVRLG---GDNLTLTEGEDISIRRVIIHPDY-------- 216

  Fly   116 VITLSSELTYTD-RITAIPLVASGEALPA------EGSEVIVA--GWGRTS-DGTNSYKIRQISL 170
                |:...|.| .:..:...|..|..|.      |.:..:|.  |:|:|| .|.:|.::.::.|
  Fly   217 ----SASTAYNDIALLELETAAKPELKPTCIWTQKEVTNTLVTAIGYGQTSFAGLSSAQLLKVPL 277

  Fly   171 KVAPEATCLDAYSDHDEQSFCLAHELKEG-------TCHGDGGGGAIYGNTLIGLTNFVVG---- 224
            |......|...|.........|..::..|       ||.||.||..:..:.|:|   :|||
  Fly   278 KSVSNEECQHHYQKDQLAQGVLGTQMCAGDITGERDTCQGDSGGPLLMQDGLLG---YVVGITSL 339

  Fly   225 --ACGSRYPDVFVRLSSYADWIQ 245
              .|.|..|.|:.|:||:.|||:
  Fly   340 GQGCASGPPSVYTRVSSFVDWIE 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	59/218 (27%)
sphe	NP_573148.2	Tryp_SPc	42..244	CDD:214473	57/215 (27%)
spirit	NP_001162707.1	CLIP	51..98	CDD:197829
		Tryp_SPc	132..364	CDD:238113	59/218 (27%)
		Tryp_SPc	132..361	CDD:214473	57/215 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437067
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840