Protein Alignment sphe and Klk12

DIOPT Version :10

• Sequence 1: NP_573148.2
• Gene: sphe / 32648
• FlyBaseID: FBgn0030774
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_001100978.2
• Gene: Klk12 / 308564
• RGDID: 1308975
• Length: 247
• Species: Rattus norvegicus
• Alignment Length: 253
• Identity: 64/253 - (25%)
• Similarity: 113/253 - (44%)
• Gaps: 35/253 - (13%)

  Fly    11 LIGLTAVGMCHA-QGRIMGGEDADATATTFTASLRVDNAHVCGGSILSQTKILTTAHCVHRDGKL 74
            |:.|..||:..| :.:|..|.:....:..:...|.......|||.::.:..:||.|||   .||.
  Rat     6 LLLLCVVGLSQADREKIYNGVECVKNSQPWQVGLFHGKYLRCGGVLVDRKWVLTAAHC---SGKY 67

  Fly    75 IDASRLACRVGSTNQYAGGKIVNVESVAV------HPDYY----NLNNNLAVITLSS--ELTYTD 127
            :      .|:|   :::..|:...|.:.:      ||.|:    |..::|.::.|:.  .|||..
  Rat    68 M------VRLG---EHSLSKLDLTEQLRLTTFSITHPSYHGAYQNHEHDLRLLRLNRPISLTYAV 123

  Fly   128 RITAIPLVASGEALPAEGSEVIVAGWGRTSDGTNSY--KIRQISLKVAPEATCLDAYSDH-DEQS 189
            |..|:|     .:....|::..::|||.|:...:.:  :::.:.|.:....||...:... .|..
  Rat   124 RPVALP-----SSCAPTGAKCHISGWGTTNKPWDPFPDRLQCLDLSIVSNETCRAVFPGRVTENM 183

  Fly   190 FCLAHELKEGTCHGDGGGGAIYGNTLIGLTNF-VVGACGSR-YPDVFVRLSSYADWIQ 245
            .|...|..:..|.||.||..:.|..|.||.:: .||.||.: .|.|:.::..|.|||:
  Rat   184 LCAGGEAGKDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQKGIPGVYTKVCKYTDWIR 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	57/221 (26%)
Klk12	NP_001100978.2	Tryp_SPc	21..240	CDD:214473	57/235 (24%)