Protein Alignment sphe and GZMM

DIOPT Version :10

• Sequence 1: NP_573148.2
• Gene: sphe / 32648
• FlyBaseID: FBgn0030774
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_005308.2
• Gene: GZMM / 3004
• HGNCID: 4712
• Length: 257
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 71/257 - (27%)
• Similarity: 121/257 - (47%)
• Gaps: 29/257 - (11%)

  Fly     6 LVILGLIGLTAVGMCHAQGRIMGGEDADATATTFTASLRVDNAHVCGGSILSQTKILTTAHCVHR 70
            |::|.| |..:||..... :|:||.:....:..:.|||:.:.:|:|||.::....:||.|||:
Human     8 LLVLAL-GALSVGSSFGT-QIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCL-- 68

  Fly    71 DGKLIDASRLA---CRVGSTNQYAGGKIVNVESVAVHPDYY---NLNNNLAVITLSSEL--TYTD 127
                  |.|:|   ..:|.....:.|...::::...||.|.   .|.|:||::.|..::  :.|.
Human    69 ------AQRMAQLRLVLGLHTLDSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTI 127

  Fly   128 RITAIPLVASGEALPAEGSEVIVAGWGRTSDGTN-SYKIRQISLKVAPEATCLDAYSDHDEQS-- 189
            |..|:|   |...:.|.|:...:||||.|..|.. |..:|::.|:|.....|.::...:...|
Human   128 RPLALP---SKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPS 189

  Fly   190 -FCLAHELK-EGTCHGDGGGGAI--YGNTLIGLTNFVVGACGSRY-PDVFVRLSSYADWIQE 246
             .|||.:.| :..|.||.||..:  .|..|..:.:|....|...: |.|...::.|..||::
Human   190 MVCLAADSKDQAPCKGDSGGPLVCGKGRVLARVLSFSSRVCTDIFKPPVATAVAPYVSWIRK 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	61/221 (28%)
GZMM	NP_005308.2	Tryp_SPc	26..252	CDD:238113	65/237 (27%)