DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sphe and Klk10

DIOPT Version :9

Sequence 1:	NP_573148.2	Gene:	sphe / 32648	FlyBaseID:	FBgn0030774	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_001004100.1	Gene:	Klk10 / 292850	RGDID:	1303242	Length:	279	Species:	Rattus norvegicus

Alignment Length:	267	Identity:	64/267 - (23%)
Similarity:	113/267 - (42%)	Gaps:	40/267 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LIGLTAVGMCHAQGRIMGG----EDADATAT-------TFTASLRVDNAHVCGGSILSQTKILTT 64
            |:.|..:.:..||..::.|    ||.:|..|       .:..||..:....|.|.::.|..:||.
  Rat    21 LLPLLMMQLWAAQALLLPGNTTREDLEAFGTLCPSVSQPWQVSLFHNLQFQCAGVLVDQNWVLTA 85

  Fly    65 AHCVHRDGKLIDASRLACRVGSTN--QYAGGKIVNVESVAVHPDYYNLN----------NNLAVI 117
            |||...       ..|..|||..:  .:...::.:..|...||.|...:          ::|.::
  Rat    86 AHCWRN-------KPLRARVGDDHLLLFQSEQLRSTNSPVFHPKYQPCSGPVLPLRSDEHDLMML 143

  Fly   118 TLSSELTYTDRITAIPLVASGEALPAEGSEVIVAGWGRTSDGTNSYKIRQIS---LKVAPEATCL 179
            .|||.:..|.::..:.|.... |.|.:  |..|:|||.|::....|. |.:|   :.:..:..|.
  Rat   144 KLSSPVVLTSKVHPVQLPFQC-AQPRQ--ECQVSGWGTTANRRVKYN-RSLSCSRVTLLSQKQCE 204

  Fly   180 DAYSD-HDEQSFCLAHELKEGTCHGDGGGGAIYGNTLIGLTNFVVGACG--SRYPDVFVRLSSYA 241
            ..|.. ......|...:..:.:|..|.||..:..|||.|:.::.:..||  ::||.|:.::.:|.
  Rat   205 TFYPGVITNNMICAGMDRDQDSCQSDSGGPLVCDNTLHGILSWSIYPCGAATQYPAVYAKICNYT 269

  Fly   242 DWIQEQI 248
            :||:..|
  Rat   270 NWIRRVI 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	54/222 (24%)
sphe	NP_573148.2	Tryp_SPc	42..244	CDD:214473	52/219 (24%)
Klk10	NP_001004100.1	Tryp_SPc	50..272	CDD:214473	53/232 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010