Protein Alignment sphe and Tmprss5

DIOPT Version :10

• Sequence 1: NP_573148.2
• Gene: sphe / 32648
• FlyBaseID: FBgn0030774
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_695223.2
• Gene: Tmprss5 / 266681
• RGDID: 628625
• Length: 445
• Species: Rattus norvegicus
• Alignment Length: 264
• Identity: 66/264 - (25%)
• Similarity: 127/264 - (48%)
• Gaps: 55/264 - (20%)

  Fly    20 CHAQ---GRIMGGEDADATATTFTASLRVDNAHVCGGSILSQTKILTTAHCVHRDGKLIDASRLA 81
            |.|:   .||:||:...:....:.||:.:.:.|.||.|:|:...::|.|||::       :.||:
  Rat   199 CGARPLASRIVGGQAVASGRWPWQASVMLGSRHTCGASVLAPYWVVTAAHCMY-------SFRLS 256

  Fly    82 CRVGSTNQYAGGKIVN-----------VESVAVHPDY--YNLNNNLAVITLSSELTYTDRITAIP 133
             |:.|...:||  :|:           ||.:..||.|  .|.:.::|::.|.:.:.::|.::|:.
  Rat   257 -RLSSWRVHAG--LVSHSAVRQHQGTMVEKIIPHPLYSAQNHDYDVALLQLRTPINFSDTVSAVC 318

  Fly   134 LVASGEALPAEGSEVIVAGWGRTSDGTNSYKIRQISLKVAP-------EATCLDAYSDHDEQSFC 191
            |.|..:..| :||:..|:|||.| |.::::....:...:.|       .::|:  ||.      .
  Rat   319 LPAKEQHFP-QGSQCWVSGWGHT-DPSHTHSSDTLQDTMVPLLSTDLCNSSCM--YSG------A 373

  Fly   192 LAHEL--------KEGTCHGDGGGGAI--YGNT--LIGLTNFVVGACGSRYPDVFVRLSSYADWI 244
            |.|.:        :...|.||.||..:  .|:|  |:|:.::..|......|.|:.:::.:.|||
  Rat   374 LTHRMLCAGYLDGRADACQGDSGGPLVCPSGDTWHLVGVVSWGRGCAEPNRPGVYAKVAEFLDWI 438

  Fly   245 QEQI 248
            .:.:
  Rat   439 HDTV 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	59/236 (25%)
Tmprss5	NP_695223.2	SRCR_2	106..203	CDD:464747	2/3 (67%)
		Tryp_SPc	208..441	CDD:238113	63/252 (25%)