Protein Alignment sphe and Klk8

DIOPT Version :10

• Sequence 1: NP_573148.2
• Gene: sphe / 32648
• FlyBaseID: FBgn0030774
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_032966.1
• Gene: Klk8 / 259277
• MGIID: 1343327
• Length: 260
• Species: Mus musculus
• Alignment Length: 258
• Identity: 61/258 - (23%)
• Similarity: 111/258 - (43%)
• Gaps: 25/258 - (9%)

  Fly     2 MQPRLVILGLIGLTAVGMCHAQG-RIMGGEDADATATTFTASLRVDNAHVCGGSILSQTKILTTA 65
            :||.:::|..:|..| |:..||| :|:.|.:....:..:.|:|......:|||.::....:||.|
Mouse     9 IQPWILLLLFMGAWA-GLTRAQGSKILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAA 72

  Fly    66 HCVHRDGKLIDASRLACRVGSTNQYAGG---KIVNVESVAVHPDYYNLN-----NNLAVITLSSE 122
            ||        ...:.:.|:|..:..:..   :.:.|.....||.|.|.|     :::.:|.|.:.
Mouse    73 HC--------KKQKYSVRLGDHSLQSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNS 129

  Fly   123 LTYTDRITAIPLVASGEALPAEGSEVIVAGWGRTSDGTNSY--KIRQISLKVAPEATCLDAYSDH 185
            ....|::..:.|   ....|..|.:.|::|||..:....::  .:....:|:..:..|..||...
Mouse   130 ANLGDKVKPVQL---ANLCPKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGK 191

  Fly   186 -DEQSFCLAHELKEGTCHGDGGGGAIYGNTLIGLTNFVVGACGS-RYPDVFVRLSSYADWIQE 246
             .|...|........||.||.||..:....|.|:|::....||. ..|.|:.::..|..||::
Mouse   192 ITEGMVCAGSSNGADTCQGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	49/217 (23%)
Klk8	NP_032966.1	Tryp_SPc	32..252	CDD:214473	50/230 (22%)