DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sphe and CG30091

DIOPT Version :9

Sequence 1:	NP_573148.2	Gene:	sphe / 32648	FlyBaseID:	FBgn0030774	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster

Alignment Length:	243	Identity:	59/243 - (24%)
Similarity:	106/243 - (43%)	Gaps:	26/243 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 RIMGGEDADATATTFTASLRVDNAHVCGGSILSQTKILTTAHCVHRDGK-LIDASRLACRVGSTN 88
            :|:||.||......:.|.::.::..:||||:::...:||.|||:..|.: ::..::|...:|..:
  Fly    36 KIVGGVDAGELKNPWMALIKTNDEFICGGSVITNKFVLTAAHCMCTDEECIVKYTQLTVTLGVYH 100

  Fly    89 QYAGG------KIVNVESVAVHPDY--YNLNNNLAVITLSSELTYTDRITAIPLVASGEALPAEG 145
            ..|.|      :|.|||.|.:|..:  .|..|::|::.|...:.|..:|..:.::.:.:..|...
  Fly   101 LLATGEHNHPHEIYNVERVYIHDSFAIQNYRNDIALLRLQKSIVYKPQIKPLCILLNDQLKPQTD 165

  Fly   146 --SEVIVAGWGRTSDGTNSYKIRQISLKVAPEATCLDAY-SDHDEQSFCLAHELKEGTCHGDGGG 207
              .|....|||.|.:|..|..::.:.:.......|..|: ...|...||....:...||..|.||
  Fly   166 LIQEFTAIGWGVTGNGKMSNNLQMVKIYRIDRKMCEAAFWYTFDYPMFCAGTAVGRDTCKRDSGG 230

  Fly   208 --------GAIYGNTLIGLTNFVVGACG--SRYPDVFVRLSSYADWIQ 245
                    ..|...|.:|:.:.....|.  ..|.||.    .:.|:|:
  Fly   231 PLYIHMLFDGIKRATQLGIVSTGTEDCRGFGMYTDVM----GHIDFIE 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	53/226 (23%)
sphe	NP_573148.2	Tryp_SPc	42..244	CDD:214473	52/223 (23%)
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	58/240 (24%)
		Tryp_SPc	37..276	CDD:238113	59/242 (24%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436539
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840