Protein Alignment sphe and TPSD1

DIOPT Version :10

• Sequence 1: NP_573148.2
• Gene: sphe / 32648
• FlyBaseID: FBgn0030774
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_036349.1
• Gene: TPSD1 / 23430
• HGNCID: 14118
• Length: 242
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 61/235 - (25%)
• Similarity: 101/235 - (42%)
• Gaps: 32/235 - (13%)

  Fly     1 MMQPRLVILGLIGL----------TAVGMCHAQGRIMGGEDADATATTFTASLRVDN---AHVCG 52
            ::.|:::.|.|:.|          .|.|....|..|:||::|..:...:..||||..   .|.||
Human     3 LLAPQMLSLLLLALPVLASPAYVAPAPGQALQQTGIVGGQEAPRSKWPWQVSLRVRGPYWMHFCG 67

  Fly    53 GSILSQTKILTTAHCVHRDGKLIDASRLACRVGSTNQYAGGKIVNVESVAVHPDYYNLNN--NLA 115
            ||::....:||.||||..|.|  |.:.|..::...:.|...:::.|..:.|||.:|.:..  ::|
Human    68 GSLIHPQWVLTAAHCVEPDIK--DLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIA 130

  Fly   116 VITLSSELTYTDRITAIPLVASGEALPAEGSEVIVAGWGRTSDGTN---SYKIRQISLKVAPEAT 177
            ::.|...:..:..|..:.|..:.|..| .|....|.|||...:..:   .|.::::.:.|.....
Human   131 LLELEEPVNISSHIHTVTLPPASETFP-PGMPCWVTGWGDVDNNVHLPPPYPLKEVEVPVVENHL 194

  Fly   178 CLDAYSD--HDEQSF--------CLAHELKEGTCHGDGGG 207
            |...|..  |...||        |...| ...:|.||.||
Human   195 CNAEYHTGLHTGHSFQIVRDDMLCAGSE-NHDSCQGDSGG 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	50/184 (27%)
TPSD1	NP_036349.1	Tryp_SPc	38..242	CDD:238113	54/200 (27%)