Protein Alignment sphe and Klk1b21

DIOPT Version :10

• Sequence 1: NP_573148.2
• Gene: sphe / 32648
• FlyBaseID: FBgn0030774
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: XP_011249110.1
• Gene: Klk1b21 / 16616
• MGIID: 892022
• Length: 296
• Species: Mus musculus
• Alignment Length: 290
• Identity: 66/290 - (22%)
• Similarity: 103/290 - (35%)
• Gaps: 81/290 - (27%)

  Fly    23 QGRIMGGEDADATATTFTASLRVDNAHVCGGSILSQTKILTTAHCVHRDGKLIDASRLACRVGST 87
            |.||:||.:.:..:..:..::...|.::|||.:|:...:||.|||..               .:|
Mouse    22 QSRIVGGFNCEKNSQPWHVAVFRYNKYICGGVLLNPNWVLTAAHCYG---------------NAT 71

  Fly    88 NQY----AGGKIVNVESVA---------VHPDYY-------------NLNNNLAVITLSSELTYT 126
            :||    ...|:...||.|         .||||.             :.:|:|.::.||.....|
Mouse    72 SQYNVWLGKNKLFQHESSAQHRLVSKSFPHPDYNMSLMNDHTPHPEDDYSNDLMLLRLSKPADIT 136

  Fly   127 DRITAIPLVASGEALPAEGSEVIVAGWGRTSDGTNSYKIRQIS---------------------- 169
            |.:..|.|....   |..||..:.:|||..:........|.|:
Mouse   137 DAVKPIDLPTEE---PKLGSTCLASGWGSITPTKCESAPRNIARCRGGAEGPGLGPVHHPLSLSS 198

  Fly   170 ------------LKVAPEATCLDAYSDHDEQSFCLAHELKEG--TCHGDGGGGAIYGNTLIGLTN 220
                        :|..|...|..||..........|.|:..|  ||.||.||..|....|.|:|:
Mouse   199 TGQIPNDLQCGFIKPLPNENCAKAYIHKVTDVMLCAGEMGGGKDTCAGDSGGPLICDGVLQGITS 263

  Fly   221 FVVGACGS-RYPDVFVRLSSYADWIQEQIA 249
            :....|.. ..|.::.:|..:..||::.:|
Mouse   264 WGSIPCAKPNAPAIYTKLIKFTSWIKDTMA 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	60/267 (22%)
Klk1b21	XP_011249110.1	Tryp_SPc	25..291	CDD:238113	63/283 (22%)