Protein Alignment sphe and Klk1

DIOPT Version :10

• Sequence 1: NP_573148.2
• Gene: sphe / 32648
• FlyBaseID: FBgn0030774
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_034769.4
• Gene: Klk1 / 16612
• MGIID: 102850
• Length: 261
• Species: Mus musculus
• Alignment Length: 275
• Identity: 70/275 - (25%)
• Similarity: 116/275 - (42%)
• Gaps: 48/275 - (17%)

  Fly     5 RLVILGLIGLTAVGMCHA---QGRIMGGEDADATATTFTASLRVDNAHVCGGSILSQTKILTTAH 66
            |.:|| .:.|:..|:..|   |.||:||.:.:..:..:..::.....:.|||.:|:...:||.||
Mouse     2 RFLIL-FLALSLGGIDAAPPVQSRIVGGFNCEKNSQPWQVAVYRFTKYQCGGILLNANWVLTAAH 65

  Fly    67 CVHRD------GK---LIDASRLACRVGSTNQYAGGKIVNVESVAVHPDYY-------------N 109
            | |.|      ||   |.|......|:             |.....|||:.             :
Mouse    66 C-HNDKYQVWLGKNNFLEDEPSAQHRL-------------VSKAIPHPDFNMSLLNEHTPQPEDD 116

  Fly   110 LNNNLAVITLSSELTYTDRITAIPLVASGEALPAEGSEVIVAGWGRTSDGTNSY--KIRQISLKV 172
            .:|:|.::.|......||.:..|.|....   |..||..:.:|||..:.....|  :::.::||:
Mouse   117 YSNDLMLLRLKKPADITDVVKPIDLPTEE---PKLGSTCLASGWGSITPVKYEYPDELQCVNLKL 178

  Fly   173 APEATCLDAYSDHDEQSFCLAHELKEG--TCHGDGGGGAIYGNTLIGLTNFVVGACGS-RYPDVF 234
            .|...|..|:.:........|.::..|  ||.||.||..|....|.|:|::....||. ..|.::
Mouse   179 LPNEDCAKAHIEKVTDDMLCAGDMDGGKDTCAGDSGGPLICDGVLQGITSWGPSPCGKPNVPGIY 243

  Fly   235 VRLSSYADWIQEQIA 249
            .|:.::..||:|.:|
Mouse   244 TRVLNFNTWIRETMA 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	57/231 (25%)
Klk1	NP_034769.4	Tryp_SPc	24..253	CDD:214473	59/245 (24%)