Protein Alignment sphe and CTRB1

DIOPT Version :10

• Sequence 1: NP_573148.2
• Gene: sphe / 32648
• FlyBaseID: FBgn0030774
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_001897.4
• Gene: CTRB1 / 1504
• HGNCID: 2521
• Length: 263
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 58/234 - (24%)
• Similarity: 112/234 - (47%)
• Gaps: 14/234 - (5%)

  Fly    25 RIMGGEDADATATTFTASLRVDNA-HVCGGSILSQTKILTTAHCVHRDGKLIDASRLACRVGSTN 88
            ||:.||||...:..:..||:.... |.||||::|:..::|.|||..|...::.|...  ..||..
Human    33 RIVNGEDAVPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVRTSDVVVAGEF--DQGSDE 95

  Fly    89 QYAGGKIVNVESVAVHPDY--YNLNNNLAVITLSSELTYTDRITAIPLVASGEALPAEGSEVIVA 151
            :..  :::.:..|..:|.:  ..:||::.::.|::...::..::|:.|.::.:..|| |:.....
Human    96 ENI--QVLKIAKVFKNPKFSILTVNNDITLLKLATPARFSQTVSAVCLPSADDDFPA-GTLCATT 157

  Fly   152 GWGRTSDGTNSY--KIRQISLKVAPEATCLDAYSDHDEQSFCLAHELKEGTCHGDGGGGAIYGN- 213
            |||:|....|..  |::|.:|.:...|.|..::..........|......:|.||.||..:...
Human   158 GWGKTKYNANKTPDKLQQAALPLLSNAECKKSWGRRITDVMICAGASGVSSCMGDSGGPLVCQKD 222

  Fly   214 ---TLIGLTNFVVGACGSRYPDVFVRLSSYADWIQEQIA 249
               ||:|:.::....|.:..|.|:.|::....|:|:.:|
Human   223 GAWTLVGIVSWGSDTCSTSSPGVYARVTKLIPWVQKILA 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	51/213 (24%)
CTRB1	NP_001897.4	Tryp_SPc	34..259	CDD:238113	56/229 (24%)