Protein Alignment sphe and Cfd

DIOPT Version :10

• Sequence 1: NP_573148.2
• Gene: sphe / 32648
• FlyBaseID: FBgn0030774
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_038487.1
• Gene: Cfd / 11537
• MGIID: 87931
• Length: 259
• Species: Mus musculus
• Alignment Length: 255
• Identity: 81/255 - (31%)
• Similarity: 126/255 - (49%)
• Gaps: 29/255 - (11%)

  Fly     6 LVILGLIGLTAVGMCHAQ--GRIMGGEDADATATTFTASLRVDNAHVCGGSILSQTKILTTAHCV 68
            |||||      ..:|.||  |||:||::|.|.|..:.||::|:..|||||::|.:..:|:.|||:
Mouse    10 LVILG------AAVCAAQPRGRILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCM 68

  Fly    69 HRDGKLIDASRLACRVGSTNQYAG---GKIVNVESVAVHPDYY--NLNNNLAVITLSSELTYTDR 128
              || :.|...:...:|:.:..|.   .:..:|:||..||...  :|.::|.:..||...:....
Mouse    69 --DG-VTDDDSVQVLLGAHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPH 130

  Fly   129 ITAIPL-VASGEALPAEGSEVIVAGWG-RTSDGTNSYKIRQISLKVAPEATC-LDAYSDHDE--- 187
            :..:|| ....|..|  |:...||||| .|..|.....:.|:.:.:....|| |..|  ||.
Mouse   131 VRPLPLQYEDKEVEP--GTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTY--HDGVVT 191

  Fly   188 -QSFCLAHELKEGTCHGDGGGGAIYGNTLIGLTNFVVGACGS-RYPDVFVRLSSYADWIQ 245
             ...| |...:..||.||.|...:.|:.:.|:..:....||: :.|.|:.|:|||..||:
Mouse   192 INMMC-AESNRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIE 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	64/217 (29%)
Cfd	NP_038487.1	Tryp_SPc	26..252	CDD:238113	71/233 (30%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		0/3 (0%)