Protein Alignment sphe and KLK8

DIOPT Version :10

• Sequence 1: NP_573148.2
• Gene: sphe / 32648
• FlyBaseID: FBgn0030774
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 140
• Identity: 34/140 - (24%)
• Similarity: 50/140 - (35%)
• Gaps: 31/140 - (22%)

  Fly     7 ASLVLTIIFSQSLCCTMIYLLYAVFCSKRIAFRPS---LSIFYCRFIIDVFLTLSAAFNQYVLFG 68
            |:|:..:.||      ::|  :.:|.:.....|||   .|.||..|:.......:||
Human   192 ATLLRDVPFS------IVY--FPLFANLNQLGRPSSEEKSPFYVSFLAGCVAGSAAA-------- 240

  Fly    69 YCGNSID-VPLECDDFKCTVNSCYYNYYL-------TQEQIVHFVIGAMTVILCARLFIMYLTAK 125
            ...|..| |.......:..||...|:.:|       ..|....|:.||    .|..|.|..|...
Human   241 VAVNPCDVVKTRLQSLERGVNEDTYSGFLDCARKIWRHEGPSAFLKGA----YCRALVIAPLFGI 301

  Fly   126 SEVTKFLSQA 135
            ::|..||..|
Human   302 AQVVYFLGIA 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	25/102 (25%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	29/124 (23%)