Protein Alignment sphe and KLK11

DIOPT Version :9

• Sequence 1: NP_573148.2
• Gene: sphe / 32648
• FlyBaseID: FBgn0030774
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 64/275 - (23%)
• Similarity: 124/275 - (45%)
• Gaps: 42/275 - (15%)

  Fly     5 RLVILGLIGLTAVGMCHAQGRIMGGEDADATATTFTASLRVDNAHVCGGSILSQTKILTTAHCVH 69
            :|::|.|    |.|:...:.||:.|.:....:..:.|:|......:||.::::...:||.|||:.
Human    37 QLILLAL----ATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLK 97

  Fly    70 RDGKLIDASRLACRVGSTN---QYAGGKIVNV------------------ESVAVHPDYYNL--- 110
            ....|...:.::..:.|:|   .:....||::                  ||.. ||.:.|.
Human    98 PWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFP-HPGFNNSLPN 161

  Fly   111 ---NNNLAVITLSSELTYTDRITAIPLVASGEALPAEGSEVIVAGWGRTSDG--TNSYKIRQISL 170
               .|::.::.::|.::.|..:.  ||..|...:.| |:..:::|||.||..  ...:.:|..::
Human   162 KDHRNDIMLVKMASPVSITWAVR--PLTLSSRCVTA-GTSCLISGWGSTSSPQLRLPHTLRCANI 223

  Fly   171 KVAPEATCLDAYSDHDEQSFCLAHELKEG---TCHGDGGGGAIYGNTLIGLTNFVVGACG-SRYP 231
            .:.....|.:||..:...:...| .::||   :|.||.||..:...:|.|:.::....|. :|.|
Human   224 TIIEHQKCENAYPGNITDTMVCA-SVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKP 287

  Fly   232 DVFVRLSSYADWIQE 246
            .|:.::..|.|||||
Human   288 GVYTKVCKYVDWIQE 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	55/238 (23%)
		Tryp_SPc	42..244	CDD:214473	51/234 (22%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	55/251 (22%)
		Tryp_SPc	54..303	CDD:238113	58/254 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920