DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sphe and CG42694

DIOPT Version :9

Sequence 1:	NP_573148.2	Gene:	sphe / 32648	FlyBaseID:	FBgn0030774	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_001188994.1	Gene:	CG42694 / 10178792	FlyBaseID:	FBgn0261584	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	215	Identity:	43/215 - (20%)
Similarity:	82/215 - (38%)	Gaps:	27/215 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 DNAHV-CGGSILSQTKILTTAHCVHRDGKLIDASRLACRVGSTNQYAGGKIVNVESVAVHPDY-- 107
            :..|| |.||::|:..:|:.|.|:...|||.      .::|.:|.........|.:|.: |.:
  Fly    52 NGTHVLCSGSLISKQFVLSAAQCIDVHGKLF------VQLGVSNATKSPHWYTVSNVVI-PSHSG 109

  Fly   108 YNLNNNLAVITLSSELTYTDRITAIPLVASGEALPAEG--SEVIVAGWGRTSDGTNSYKIRQISL 170
            ..|..::.::.||..:.|.|.:..|.:..:...|....  .....:.|...:....:..:.|:|
  Fly   110 KRLQRDIGLLKLSQSVDYNDFVYPICIALNTNTLDMVKILQNFTTSAWLSKNKNPQTIVLSQLS- 173

  Fly   171 KVAPEATC-LDAYSDHDEQSFCLAHELKEGTCHGDGG---------GGAIYGNTLIGLTNFVVGA 225
                ...| |:...:...:..|.|...:..:|..|.|         |..|....|.|:..:|.|.
  Fly   174 ----RDRCKLNLSGNVTPKEICAASLQRNNSCFIDSGSALTQPIIQGSNIVREMLFGIRGYVNGR 234

  Fly   226 CGSRYPDVFVRLSSYADWIQ 245
            .....|.:::.::....||:
  Fly   235 SWCSEPAIYIDVAECVGWIE 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	43/215 (20%)
sphe	NP_573148.2	Tryp_SPc	42..244	CDD:214473	41/212 (19%)
CG42694	NP_001188994.1	Tryp_SPc	46..256	CDD:304450	43/215 (20%)
		Tryp_SPc	46..253	CDD:214473	41/212 (19%)
		Tryp_SPc	319..505	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436543
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930