DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9676 and prss60.1

DIOPT Version :9

Sequence 1:	NP_728008.1	Gene:	CG9676 / 32647	FlyBaseID:	FBgn0030773	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	266	Identity:	88/266 - (33%)
Similarity:	132/266 - (49%)	Gaps:	41/266 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LVLCAAGVLAQ-NDSVVEP---RIVGGTKAREGQFPHQISLRR--RGSHTCGGSIISKDYVVTAA 67
            |:||..|..:| |...:.|   |||||..|.:|.:|.|:||..  .|.|.||||:|:.::|:|||
Zfish    11 LLLCVQGSHSQLNVCGLAPLNNRIVGGVNAFDGSWPWQVSLHSPIYGGHFCGGSLINSEWVLTAA 75

  Fly    68 HCVKQGNNVAPANELEIQAGSLLLSSG-----GVRV-----PVATVTVHPNYN--SNGHDVAVLR 120
            ||:.:           |...|||:..|     ||..     .|:.:||||:||  :|.:|:|:|.
Zfish    76 HCLPR-----------ITTSSLLVFLGKTTQQGVNTYEINRTVSVITVHPSYNNLTNENDIALLH 129

  Fly   121 LRNSLTFNSNIAAIKLATEDP--PNDATVDISGWGAISQRG---PISNSLLYVQVKALSRESCQK 180
            |.:::||::.|..:.||.::.  ||..:..|:|||.| |.|   |....|....:..:..:.|..
Zfish   130 LSSAVTFSNYIRPVCLAAQNSVFPNGTSSWITGWGNI-QLGVNLPAPGILQETMIPVVPNDQCNA 193

  Fly   181 TY-LRQLPETTMCL-LHPKDKGACYGDSGGPATYQGKLV----GLASFVIGGCGRAAPDGYERVS 239
            .. ...:....:|. |....:..|.||||||...:..||    |:.|:..|.....:|..|.|||
Zfish   194 LLGSGSVTNNMICAGLLQGGRDTCQGDSGGPMVSKQCLVWVQSGITSWGYGCADPYSPGVYTRVS 258

  Fly   240 KLRNWI 245
            :.::||
Zfish   259 QYQSWI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9676	NP_728008.1	Tryp_SPc	27..245	CDD:214473	79/242 (33%)
CG9676	NP_728008.1	Tryp_SPc	28..248	CDD:238113	80/243 (33%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	79/242 (33%)
		Tryp_SPc	34..267	CDD:238113	80/243 (33%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587847
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840