DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9676 and PRSS1

DIOPT Version :9

Sequence 1:	NP_728008.1	Gene:	CG9676 / 32647	FlyBaseID:	FBgn0030773	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_011514713.1	Gene:	PRSS1 / 5644	HGNCID:	9475	Length:	472	Species:	Homo sapiens

Alignment Length:	245	Identity:	70/245 - (28%)
Similarity:	114/245 - (46%)	Gaps:	18/245 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLVLCAAGVLAQNDSVVEPRIVGGTKAREGQFPHQISLRRRGSHTCGGSIISKDYVVTAAHCVKQ 72
            :|...||.:.|..|.  :.:||||....|...|:|:|| ..|.|.||||:|::.:||:|.||.|
Human   231 ILTFVAAALAAPFDD--DDKIVGGYNCEENSVPYQVSL-NSGYHFCGGSLINEQWVVSAGHCYK- 291

  Fly    73 GNNVAPANELEIQAGS---LLLSSGGVRVPVATVTVHPNYNSN--GHDVAVLRLRNSLTFNSNIA 132
                   :.::::.|.   .:|......:..|.:..||.|:..  .:|:.:::|.:....|:.::
Human   292 -------SRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVS 349

  Fly   133 AIKLATEDPPNDATVDISGWGAISQRG-PISNSLLYVQVKALSRESCQKTYLRQLPETTMCL-LH 195
            .|.|.|..|.......|||||..:..| ...:.|..:....||:..|:.:|..::.....|: ..
Human   350 TISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFL 414

  Fly   196 PKDKGACYGDSGGPATYQGKLVGLASFVIGGCGRAAPDGYERVSKLRNWI 245
            ...|.:|.||||||....|:|.|:.|:..|...:..|..|.:|.....||
Human   415 EGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWI 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9676	NP_728008.1	Tryp_SPc	27..245	CDD:214473	63/224 (28%)
CG9676	NP_728008.1	Tryp_SPc	28..248	CDD:238113	65/225 (29%)
PRSS1	XP_011514713.1	Ig	19..119	CDD:299845
		IG_like	29..113	CDD:214653
		Tryp_SPc	248..464	CDD:214473	63/224 (28%)
		Tryp_SPc	249..467	CDD:238113	65/225 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBP0
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820