DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9676 and Prss53

DIOPT Version :9

Sequence 1:	NP_728008.1	Gene:	CG9676 / 32647	FlyBaseID:	FBgn0030773	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	251	Identity:	66/251 - (26%)
Similarity:	101/251 - (40%)	Gaps:	77/251 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 GQFPHQISLRRRGSHTCGGSIISKDYVVTAAHCVKQGNNVAPANELEIQAGSLL---LSSGGVRV 98
            |::|.|.|:||:|.|.|.||:::..:|:|||||.:: ...|..:...:..|||.   ||.|...|
  Rat    46 GEWPWQASVRRQGVHICSGSLVADTWVLTAAHCFEK-MATAELSSWSVVLGSLKQEGLSPGAEEV 109

  Fly    99 PVATVTVHPNYN--SNGHDVAVLRLRNSLTFNSNIAAIKLATEDPPNDATVDISGW--------- 152
            .||.:.:...||  |.|.|:|:|:|.:.:...:  ..:...|...|..|:...:||
  Rat   110 GVAALQLPKAYNHYSQGSDLALLQLTHPIVHTT--LCLPQPTHHFPFGASCWATGWDQNTSDGKY 172

  Fly   153 -----GAISQRG-----------------------PISNSLLYVQVKALSRESCQKTYLRQLPET 189
                 ...||.|                       |:|.:|..::::.:||.:|...|.|
  Rat   173 CPRHKSRESQTGSVLTVLALCSHCVSELDSTLSPLPVSRTLRNLRLRLISRPTCNCLYNR----- 232

  Fly   190 TMCLLH------------------PKDKGACYGDSGGPATYQGK-----LVGLASF 222
                ||                  |..:|.|.||||||...:..     .||:.||
  Rat   233 ----LHQRLLANPARSGMLCGGAQPGVQGPCQGDSGGPVMCREPDGHWVQVGIISF 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9676	NP_728008.1	Tryp_SPc	27..245	CDD:214473	66/251 (26%)
CG9676	NP_728008.1	Tryp_SPc	28..248	CDD:238113	66/251 (26%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113	66/251 (26%)
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100