DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9676 and PRSS53

DIOPT Version :9

Sequence 1:	NP_728008.1	Gene:	CG9676 / 32647	FlyBaseID:	FBgn0030773	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_011544118.1	Gene:	PRSS53 / 339105	HGNCID:	34407	Length:	623	Species:	Homo sapiens

Alignment Length:	322	Identity:	81/322 - (25%)
Similarity:	124/322 - (38%)	Gaps:	92/322 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 WTSLLVLCAAGVLAQNDSVVE----PRIVGGTKARE-----GQFPHQISLRRRGSHTCGGSIISK 60
            |..:|::..|.||.:.....:    .|..|..|.:|     |::|.|.|:||:|:|.|.||:::.
Human     5 WGPVLLIAGATVLMEGLQAAQRACGQRGPGPPKPQEGNTVPGEWPWQASVRRQGAHICSGSLVAD 69

  Fly    61 DYVVTAAHCVKQGNNVAPANEL---EIQAGSLL---LSSGGVRVPVATVTVHPNYN--SNGHDVA 117
            .:|:|||||.::    |.|.||   .:..|||.   ||.|...|.||.:.:...||  |.|.|:|
Human    70 TWVLTAAHCFEK----AAATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYSQGSDLA 130

  Fly   118 VLRLRNSLTFNSNIAAIKLATEDP----PNDATVDISGWGAISQRG------------------- 159
            :|:|.:..|..      .|....|    |..|:...:||...:..|
Human   131 LLQLAHPTTHT------PLCLPQPAHRFPFGASCWATGWDQDTSDGKCWPRLKLGEALCLPSVTV 189

  Fly   160 --------------------------PISNSLLYVQVKALSRESCQKTYLRQLPETTMC------ 192
                                      |...:|..::::.:||.:|...| .||.:..:.
Human   190 SAPNCPGFQSPLLPRSQTLAPAPSLSPAPGTLRNLRLRLISRPTCNCIY-NQLHQRHLSNPARPG 253

  Fly   193 LL----HPKDKGACYGDSGGPATY---QGKLV--GLASFVIGGCGRAAPDGYERVSKLRNWI 245
            :|    .|..:|.|.||||||...   .|..|  |:.||........||......:...:|:
Human   254 MLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWL 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9676	NP_728008.1	Tryp_SPc	27..245	CDD:214473	75/294 (26%)
CG9676	NP_728008.1	Tryp_SPc	28..248	CDD:238113	75/295 (25%)
PRSS53	XP_011544118.1	Tryp_SPc	42..316	CDD:238113	72/285 (25%)
		Tryp_SPc	43..314	CDD:214473	71/281 (25%)
		Tryp_SPc	359..>512	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100