DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9676 and Tmprss6

DIOPT Version :9

Sequence 1:	NP_728008.1	Gene:	CG9676 / 32647	FlyBaseID:	FBgn0030773	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_006242057.1	Gene:	Tmprss6 / 315388	RGDID:	1307138	Length:	811	Species:	Rattus norvegicus

Alignment Length:	237	Identity:	81/237 - (34%)
Similarity:	132/237 - (55%)	Gaps:	20/237 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 RIVGGTKAREGQFPHQISLRRRGSHTCGGSIISKDYVVTAAHCVKQGNNVAPANELEIQAGSLLL 91
            |||||..:.||::|.|.||:.||.|.|||::|:..:|:|||||.::.:..:| ....:..|.:..
  Rat   576 RIVGGAMSSEGEWPWQASLQIRGRHICGGALIADRWVITAAHCFQEDSMASP-RLWTVFLGKMRQ 639

  Fly    92 SS---GGVRVPVATVTVHPNYNSNGH--DVAVLRLRNSLTFNSNIAAIKLATE----DPPNDATV 147
            :|   |.|...|:.:.:||.:..:.|  |||:|:|.:.:.:::.:..:.|...    :|.....
  Rat   640 NSRWPGEVSFKVSRLFLHPYHEEDSHDYDVALLQLDHPVVYSATVRPVCLPARSHFFEPGQHCW- 703

  Fly   148 DISGWGAISQRGPISNSLLYVQVKALSRESCQKTYLRQLPETTMCLLHPK-DKGACYGDSGGPAT 211
             |:||||..:.||.|::|..|.|:.:.::.|.:.|..|:....:|..:.| .|.||.||||||..
  Rat   704 -ITGWGAQREGGPGSSTLQKVDVQLIPQDLCNEAYRYQVTPRMLCAGYRKGKKDACQGDSGGPLV 767

  Fly   212 YQ---GK--LVGLASFVIGGCGRAAPDG-YERVSKLRNWIAE 247
            .:   |:  |.||.|:.: ||||....| |.||:::.|||.:
  Rat   768 CKEPSGRWFLAGLVSWGL-GCGRPNFFGVYTRVTRVVNWIQQ 808

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9676	NP_728008.1	Tryp_SPc	27..245	CDD:214473	79/233 (34%)
CG9676	NP_728008.1	Tryp_SPc	28..248	CDD:238113	80/236 (34%)
Tmprss6	XP_006242057.1	SEA	88..185	CDD:279699
		LDLa	459..489	CDD:238060
		LDLa	495..525	CDD:238060
		Ldl_recept_a	529..566	CDD:278486
		Tryp_SPc	576..806	CDD:214473	79/233 (34%)
		Tryp_SPc	577..809	CDD:238113	80/236 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910