DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9676 and Klkb1

DIOPT Version :9

Sequence 1:	NP_728008.1	Gene:	CG9676 / 32647	FlyBaseID:	FBgn0030773	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_036857.2	Gene:	Klkb1 / 25048	RGDID:	67382	Length:	638	Species:	Rattus norvegicus

Alignment Length:	256	Identity:	77/256 - (30%)
Similarity:	126/256 - (49%)	Gaps:	19/256 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LVLCAAGVLAQNDSVVEPRIVGGTKAREGQFPHQISLRRR---GSHTCGGSIISKDYVVTAAHCV 70
            |.||.....:...:.:..||||||.:..|::|.|:||:.:   .:|.||||||.:.:::|||||.
  Rat   372 LRLCKVVESSDCTTKINARIVGGTNSSLGEWPWQVSLQVKLVSQNHMCGGSIIGRQWILTAAHCF 436

  Fly    71 KQGNNVAPANELEIQAGSLLLSSGGVRVPVATV---TVHPNY--NSNGHDVAVLRLRNSLTFNSN 130
               :.:...:...|..|.|.||....:.|.:::   .:|..|  :...:|:|:::|:..|.:...
  Rat   437 ---DGIPYPDVWRIYGGILNLSEITNKTPFSSIKELIIHQKYKMSEGSYDIALIKLQTPLNYTEF 498

  Fly   131 IAAIKLATEDPPNDATVD--ISGWGAISQRGPISNSLLYVQVKALSRESCQKTYLRQLPETTMCL 193
            ...|.|.::...|....:  ::|||...:||...|.|....:..:..|.|||.|...:....|..
  Rat   499 QKPICLPSKADTNTIYTNCWVTGWGYTKERGETQNILQKATIPLVPNEECQKKYRDYVITKQMIC 563

  Fly   194 LHPKDKG--ACYGDSGGP--ATYQGK--LVGLASFVIGGCGRAAPDGYERVSKLRNWIAEK 248
            ...|:.|  ||.||||||  ..:.|:  |||:.|:..|...:..|..|.:|::..:||.||
  Rat   564 AGYKEGGIDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKEQPGVYTKVAEYIDWILEK 624

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9676	NP_728008.1	Tryp_SPc	27..245	CDD:214473	70/233 (30%)
CG9676	NP_728008.1	Tryp_SPc	28..248	CDD:238113	71/235 (30%)
Klkb1	NP_036857.2	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	201..284	CDD:128519
		APPLE	292..375	CDD:128519	1/2 (50%)
		Tryp_SPc	390..621	CDD:214473	70/233 (30%)
		Tryp_SPc	391..621	CDD:238113	69/232 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910