DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9676 and Klk1b4

DIOPT Version :9

Sequence 1:	NP_728008.1	Gene:	CG9676 / 32647	FlyBaseID:	FBgn0030773	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_035045.2	Gene:	Klk1b4 / 18048	MGIID:	97320	Length:	256	Species:	Mus musculus

Alignment Length:	240	Identity:	70/240 - (29%)
Similarity:	105/240 - (43%)	Gaps:	45/240 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 EGQFPHQISLRRRGSHTCGGSIISKDYVVTAAHC------VKQGNNVAPANELEIQAGS--LLLS 92
            |...|..:::.|...:.|||.::.:::|:|||||      |..|.|    |.||.:...  .|:|
Mouse    28 ENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKN----NFLEDEPSDQHRLVS 88

  Fly    93 SGGVRVPVATVTVHPNYNS---NGH----------DVAVLRLRNSLTFNSNIAAIKLATEDPPND 144
            ..   :|      ||::|.   |.|          |:.:|||.........:..|.|.||:|...
Mouse    89 KA---IP------HPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLG 144

  Fly   145 ATVDISGWGAISQRGPIS----NSLLYVQVKALSRESCQKTYLRQLPETTMCLLHPKDKGA--CY 203
            :|...||||:.:   ||.    :.|..|.:|.|..|.|.|.:..::.:..:| ....|.|:  |.
Mouse   145 STCLASGWGSTT---PIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLC-AGEMDGGSYTCE 205

  Fly   204 GDSGGPATYQGKLVGLASFVIGGCGR-AAPDGYERVSKLRNWIAE 247
            .|||||....|.|.|:.|:....||. ..|..|.::.|..:||.|
Mouse   206 HDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRE 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9676	NP_728008.1	Tryp_SPc	27..245	CDD:214473	67/236 (28%)
CG9676	NP_728008.1	Tryp_SPc	28..248	CDD:238113	70/240 (29%)
Klk1b4	NP_035045.2	Tryp_SPc	13..251	CDD:238113	70/240 (29%)
Klk1b4	NP_035045.2	Activation peptide homolog	18..24
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910